Peripheral neuropathy in subacute sclerosing panencephalitis - Immunohistochemical and ultrastructural evidence

S. K. Shankar, A. B. Taly, G. R. Arunodaya, D. Nagaraja, P. N. Jayakumar, V. Ravi

Research output: Contribution to journalArticle

Abstract

A patient with SSPE who had prominent diffuse white matter hypodensities on CT scan indicating central white matter demyelination and nerve conduction abnormalities suggestive of peripheral neuropathy is reported. Diagnosis was established by demonstration of elevated CSF measles antibody titers and presence of virus antigen and nucleocapsid in peripheral nerve. To our knowledge, this is the first report of demonstration of measles virus nucleocapsides and antigen in the peripheral nerve in SSPE.

Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalClinical Neuropathology
Volume17
Issue number1
Publication statusPublished - Jan 1998

Fingerprint

Subacute Sclerosing Panencephalitis
Peripheral Nervous System Diseases
Peripheral Nerves
Antigens
Nucleocapsid
Measles virus
Neural Conduction
Measles
Demyelinating Diseases
Viral Load
Antibodies
White Matter

Keywords

  • Immunocytochemistry
  • Measles antigen
  • Peripheral neuropathy
  • SSPE
  • Ultrastructure

ASJC Scopus subject areas

  • Clinical Neurology
  • Pathology and Forensic Medicine
  • Neuroscience(all)

Cite this

Peripheral neuropathy in subacute sclerosing panencephalitis - Immunohistochemical and ultrastructural evidence. / Shankar, S. K.; Taly, A. B.; Arunodaya, G. R.; Nagaraja, D.; Jayakumar, P. N.; Ravi, V.

In: Clinical Neuropathology, Vol. 17, No. 1, 01.1998, p. 15-18.

Research output: Contribution to journalArticle

Shankar, S. K. ; Taly, A. B. ; Arunodaya, G. R. ; Nagaraja, D. ; Jayakumar, P. N. ; Ravi, V. / Peripheral neuropathy in subacute sclerosing panencephalitis - Immunohistochemical and ultrastructural evidence. In: Clinical Neuropathology. 1998 ; Vol. 17, No. 1. pp. 15-18.
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