TY - JOUR
T1 - Partial genetic characterization of Sedlec virus (Orthobunyavirus, Bunyaviridae)
AU - Bakonyi, Tamás
AU - Kolodziejek, Jolanta
AU - Rudolf, Ivo
AU - Berčič, Rebeka
AU - Nowotny, Norbert
AU - Hubálek, Zdenek
N1 - Funding Information:
This study was partially funded by European Union Grants HEALTH.2010.2.3.3-3 Project 261391 EuroWestNile ( http://eurowestnile.isciii.es/ewn ) and FP7-261504 EDENext ( http://www.edenext.eu ) and is catalogued by the EDENext Steering Committee as EDENext129. The contents of this paper are the sole responsibility of the authors and do not necessarily reflect the views of the European Commission.
PY - 2013/8
Y1 - 2013/8
N2 - Sedlec virus (SEDV) is genetically related to Simbu group orthobunyaviruses.SEDV is genetically distinct from Schmallenberg virus.Unclassified Leanyer, I612045 and Oyo viruses are the closest relatives of SEDV.These four viruses might represent a novel serogroup of the Orthobunyavirus genus. Sedlec virus (SEDV) was isolated from the blood of a reed warbler (Acrocephalus scirpaceus) in July 1984 in South Moravia, Czech Republic. In this study first genetic data of SEDV are presented which allow an estimate on its phylogenetic and taxonomic positioning within the genus Orthobunyavirus. The phylogenetic analysis of a 369. nt long stretch within the S segment (nucleocapsid protein gene and non-structural S protein gene) indicates genetic relatedness of SEDV to Leanyer virus and Simbu group viruses, while the phylogenetic tree based on 1796. nt long sequences of the L segment (RNA-dependent RNA polymerase gene) demonstrates genetic relationship of SEDV to two yet unclassified orthobunyaviruses: I612045 virus (isolated in India in 1961) and Oyo virus (isolated in Nigeria in 1964). Considering the genetic distances and the phylogenetic analyses, SEDV might represent a novel serogroup of the Orthobunyavirus genus.
AB - Sedlec virus (SEDV) is genetically related to Simbu group orthobunyaviruses.SEDV is genetically distinct from Schmallenberg virus.Unclassified Leanyer, I612045 and Oyo viruses are the closest relatives of SEDV.These four viruses might represent a novel serogroup of the Orthobunyavirus genus. Sedlec virus (SEDV) was isolated from the blood of a reed warbler (Acrocephalus scirpaceus) in July 1984 in South Moravia, Czech Republic. In this study first genetic data of SEDV are presented which allow an estimate on its phylogenetic and taxonomic positioning within the genus Orthobunyavirus. The phylogenetic analysis of a 369. nt long stretch within the S segment (nucleocapsid protein gene and non-structural S protein gene) indicates genetic relatedness of SEDV to Leanyer virus and Simbu group viruses, while the phylogenetic tree based on 1796. nt long sequences of the L segment (RNA-dependent RNA polymerase gene) demonstrates genetic relationship of SEDV to two yet unclassified orthobunyaviruses: I612045 virus (isolated in India in 1961) and Oyo virus (isolated in Nigeria in 1964). Considering the genetic distances and the phylogenetic analyses, SEDV might represent a novel serogroup of the Orthobunyavirus genus.
KW - Acrocephalus
KW - Leanyer virus
KW - Orthobunyavirus
KW - Sedlec virus
KW - Simbu group
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U2 - 10.1016/j.meegid.2013.07.025
DO - 10.1016/j.meegid.2013.07.025
M3 - Article
C2 - 23917024
AN - SCOPUS:84884342450
SN - 1567-1348
VL - 19
SP - 244
EP - 249
JO - Infection, Genetics and Evolution
JF - Infection, Genetics and Evolution
ER -
