TY - JOUR
T1 - Paraneoplastic acral vascular syndrome
T2 - case presentation and literature review
AU - AlRasbi, Sara
AU - Al-Badi, Amira H
AU - Al Alawi, Abdullah M
N1 - © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2021/1/15
Y1 - 2021/1/15
N2 - A 65-year-old man, a smoker, presented to the emergency department with progressive digital ischaemia, fever and weight loss. The clinical examination revealed generalised lymphadenopathy and ischaemic changes of the right distal phalanges of the second, third and fourth fingers. He had an ultrasound-guided biopsy of the cervical lymph node, which showed histopathological findings of classic Hodgkin's lymphoma. Paraneoplastic acral vascular syndrome (PAVS) is a rare phenomenon and seen more in solid malignancies. There are very few reported cases of PAVS in haematological malignancies, including Hodgkin's lymphoma. This case highlights the idea that the presence of acral vascular syndrome-especially in older patients-should alert physicians to search for an underlying malignancy as part of the medical evaluation. Also, it shows that medical treatment may slow the progress of the digital ischaemia until the culprit tumour has been identified and treated.
AB - A 65-year-old man, a smoker, presented to the emergency department with progressive digital ischaemia, fever and weight loss. The clinical examination revealed generalised lymphadenopathy and ischaemic changes of the right distal phalanges of the second, third and fourth fingers. He had an ultrasound-guided biopsy of the cervical lymph node, which showed histopathological findings of classic Hodgkin's lymphoma. Paraneoplastic acral vascular syndrome (PAVS) is a rare phenomenon and seen more in solid malignancies. There are very few reported cases of PAVS in haematological malignancies, including Hodgkin's lymphoma. This case highlights the idea that the presence of acral vascular syndrome-especially in older patients-should alert physicians to search for an underlying malignancy as part of the medical evaluation. Also, it shows that medical treatment may slow the progress of the digital ischaemia until the culprit tumour has been identified and treated.
KW - Aged
KW - Fingers/blood supply
KW - Hodgkin Disease/complications
KW - Humans
KW - Male
KW - Paraneoplastic Syndromes/etiology
KW - Vascular Diseases/etiology
UR - http://www.scopus.com/inward/record.url?scp=85099689256&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85099689256&partnerID=8YFLogxK
U2 - 10.1136/bcr-2020-237258
DO - 10.1136/bcr-2020-237258
M3 - Article
C2 - 33452070
SN - 1757-790X
VL - 14
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 1
M1 - e237258
ER -