TY - JOUR
T1 - Omani experience with the use of factor IX Fc fusion protein
AU - Alzadjali, Shireen I.
AU - Wali, Yasser
N1 - Funding Information:
Contributors SIA: literature search, data acquisition, manuscript preparation, manuscript editing and manuscript review. YW: concept, patients care and follow-up, manuscript preparation, manuscript editing and manuscript review. Guarantors: both authors take responsibility for the integrity of the work as a whole from inception to published article. The manuscript has been read and approved by all the authors, requirements for authorship have been met, and each author believes that the manuscript represents honest work. Funding This study was funded by SOBI (N/A). Competing interests None declared.
Publisher Copyright:
©
PY - 2021/7/21
Y1 - 2021/7/21
N2 - We describe our local experience in the management of haemophilia B patients with factor IX Fc fusion protein. Two children with haemophilia B were managed with the use of a personalised/tailored dosing schedule of factor IX Fc fusion protein. Compared with the standard half-life factor IX, prophylaxis with factor IX Fc fusion protein was cost-effective, with much less injections, better bleeding control, improved tolerability or no inhibitor development.
AB - We describe our local experience in the management of haemophilia B patients with factor IX Fc fusion protein. Two children with haemophilia B were managed with the use of a personalised/tailored dosing schedule of factor IX Fc fusion protein. Compared with the standard half-life factor IX, prophylaxis with factor IX Fc fusion protein was cost-effective, with much less injections, better bleeding control, improved tolerability or no inhibitor development.
KW - congenital disorders
KW - haematology (incl blood transfusion)
KW - paediatrics
UR - http://www.scopus.com/inward/record.url?scp=85111116293&partnerID=8YFLogxK
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U2 - 10.1136/bcr-2020-241154
DO - 10.1136/bcr-2020-241154
M3 - Article
C2 - 34290003
AN - SCOPUS:85111116293
SN - 1757-790X
VL - 14
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 7
M1 - e241154
ER -