Ocular adnexal reactive lymphoid hyperplasia in children

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3 Citations (Scopus)

Abstract

Aim: To describe the clinical and histopathological features of ocular reactive lymphoid hyperplasia in children, and review the literature regarding this entity. Materials and Methods: In this retrospective, interventional case series, a chart review was performed of three patients diagnosed with reactive lymphoid hyperplasia. Details of clinical presentation, ocular and systemic examination findings, management and subsequent course were noted. Results: Three children, aged 9-14 years presented with ocular adnexal masses (two unilateral and one bilateral) with 7-12 months duration. Ocular examination revealed discrete nasal conjunctival masses in two patients, and bilateral eyelid fullness and conjunctival chemosis in the third patient. Systemic evaluation and laboratory tests were normal in all patients. Orbital imaging showed lacrimal gland enlargement in one patient. Histopathological evaluation with immunohistochemical markers established the diagnosis of reactive lymphoid hyperplasia. Two patients underwent surgical excision with complete resolution. All patients have remained stable and at their last follow-up have showed no evidence of recurrence, transformation, or systemic involvement. Conclusion: Reactive lymphoid hyperplasia, though uncommon in children, can have a favorable outcome with timely intervention.

Original languageEnglish
Pages (from-to)406-409
Number of pages4
JournalMiddle East African Journal of Ophthalmology
Volume19
Issue number4
DOIs
Publication statusPublished - Oct 2012

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Pseudolymphoma
Lacrimal Apparatus
Eyelids
Nose
Recurrence

Keywords

  • Children
  • Conjunctiva
  • Immunohistochemistry
  • Lacrimal Gland
  • Lymphoid Hyperplasia

ASJC Scopus subject areas

  • Ophthalmology

Cite this

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title = "Ocular adnexal reactive lymphoid hyperplasia in children",
abstract = "Aim: To describe the clinical and histopathological features of ocular reactive lymphoid hyperplasia in children, and review the literature regarding this entity. Materials and Methods: In this retrospective, interventional case series, a chart review was performed of three patients diagnosed with reactive lymphoid hyperplasia. Details of clinical presentation, ocular and systemic examination findings, management and subsequent course were noted. Results: Three children, aged 9-14 years presented with ocular adnexal masses (two unilateral and one bilateral) with 7-12 months duration. Ocular examination revealed discrete nasal conjunctival masses in two patients, and bilateral eyelid fullness and conjunctival chemosis in the third patient. Systemic evaluation and laboratory tests were normal in all patients. Orbital imaging showed lacrimal gland enlargement in one patient. Histopathological evaluation with immunohistochemical markers established the diagnosis of reactive lymphoid hyperplasia. Two patients underwent surgical excision with complete resolution. All patients have remained stable and at their last follow-up have showed no evidence of recurrence, transformation, or systemic involvement. Conclusion: Reactive lymphoid hyperplasia, though uncommon in children, can have a favorable outcome with timely intervention.",
keywords = "Children, Conjunctiva, Immunohistochemistry, Lacrimal Gland, Lymphoid Hyperplasia",
author = "Abdullah Al-Mujaini and Upender Wali and Anuradha Ganesh and Ibrahim Al-Hadabi and Ikram Burney",
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T1 - Ocular adnexal reactive lymphoid hyperplasia in children

AU - Al-Mujaini, Abdullah

AU - Wali, Upender

AU - Ganesh, Anuradha

AU - Al-Hadabi, Ibrahim

AU - Burney, Ikram

PY - 2012/10

Y1 - 2012/10

N2 - Aim: To describe the clinical and histopathological features of ocular reactive lymphoid hyperplasia in children, and review the literature regarding this entity. Materials and Methods: In this retrospective, interventional case series, a chart review was performed of three patients diagnosed with reactive lymphoid hyperplasia. Details of clinical presentation, ocular and systemic examination findings, management and subsequent course were noted. Results: Three children, aged 9-14 years presented with ocular adnexal masses (two unilateral and one bilateral) with 7-12 months duration. Ocular examination revealed discrete nasal conjunctival masses in two patients, and bilateral eyelid fullness and conjunctival chemosis in the third patient. Systemic evaluation and laboratory tests were normal in all patients. Orbital imaging showed lacrimal gland enlargement in one patient. Histopathological evaluation with immunohistochemical markers established the diagnosis of reactive lymphoid hyperplasia. Two patients underwent surgical excision with complete resolution. All patients have remained stable and at their last follow-up have showed no evidence of recurrence, transformation, or systemic involvement. Conclusion: Reactive lymphoid hyperplasia, though uncommon in children, can have a favorable outcome with timely intervention.

AB - Aim: To describe the clinical and histopathological features of ocular reactive lymphoid hyperplasia in children, and review the literature regarding this entity. Materials and Methods: In this retrospective, interventional case series, a chart review was performed of three patients diagnosed with reactive lymphoid hyperplasia. Details of clinical presentation, ocular and systemic examination findings, management and subsequent course were noted. Results: Three children, aged 9-14 years presented with ocular adnexal masses (two unilateral and one bilateral) with 7-12 months duration. Ocular examination revealed discrete nasal conjunctival masses in two patients, and bilateral eyelid fullness and conjunctival chemosis in the third patient. Systemic evaluation and laboratory tests were normal in all patients. Orbital imaging showed lacrimal gland enlargement in one patient. Histopathological evaluation with immunohistochemical markers established the diagnosis of reactive lymphoid hyperplasia. Two patients underwent surgical excision with complete resolution. All patients have remained stable and at their last follow-up have showed no evidence of recurrence, transformation, or systemic involvement. Conclusion: Reactive lymphoid hyperplasia, though uncommon in children, can have a favorable outcome with timely intervention.

KW - Children

KW - Conjunctiva

KW - Immunohistochemistry

KW - Lacrimal Gland

KW - Lymphoid Hyperplasia

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