Normal spirometric reference values for omani adults

Omar A. Al-Rawas, Sawasn Baddar, Abdullah A. Al-Maniri, Jothi Balaji, B. Jayakrishnan, Bazdawi M. Al-Riyami

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

International guidelines recommend the use of population-specific reference values to eliminate the well-recognized influence of ethnic variation on lung function. This study was designed to derive spirometric prediction equations for healthy Omani adults. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow rate (PEFR), and forced expiratory flow at 25% to 75% of FVC (FEF25-75%) were measured in 419 "healthy" nonsmoking Omani adults (256 men, 163 women), aged 18-65 years. Multiple linear regression analysis was performed for each spirometric parameter against age, height, and weight for men and women separately, and prediction equations for all the above parameters were derived and compared with values derived using equations published from other populations. All measured spirometric parameters increased with height and decreased with age, and they were all significantly higher in men. In contrast, FEV1/FVC% values decreased with height and increased with age and were higher in women. The predicted normal values of FVC and FEV1 for our subjects using the derived equations were lower by 7-17% compared with respective Caucasian values, with smaller difference in the predicted values of PEFR, FEV1/FVC%, and FEF25-75%. This report presents previously unavailable spirometric reference equations for the Omani adults. Our findings highlight the need to use reference values based on updated data derived from relevant populations.

Original languageEnglish
Pages (from-to)245-251
Number of pages7
JournalLung
Volume187
Issue number4
DOIs
Publication statusPublished - Aug 2009

Fingerprint

Vital Capacity
Reference Values
Peak Expiratory Flow Rate
Population
Forced Expiratory Volume
Linear Models
Regression Analysis
Guidelines
Weights and Measures
Lung

Keywords

  • Ethnic Arab
  • Lung function
  • Omani
  • Reference values
  • Spirometry

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Normal spirometric reference values for omani adults. / Al-Rawas, Omar A.; Baddar, Sawasn; Al-Maniri, Abdullah A.; Balaji, Jothi; Jayakrishnan, B.; Al-Riyami, Bazdawi M.

In: Lung, Vol. 187, No. 4, 08.2009, p. 245-251.

Research output: Contribution to journalArticle

Al-Rawas, Omar A. ; Baddar, Sawasn ; Al-Maniri, Abdullah A. ; Balaji, Jothi ; Jayakrishnan, B. ; Al-Riyami, Bazdawi M. / Normal spirometric reference values for omani adults. In: Lung. 2009 ; Vol. 187, No. 4. pp. 245-251.
@article{4163ebd8839d4b84a92d2e07bd1cad96,
title = "Normal spirometric reference values for omani adults",
abstract = "International guidelines recommend the use of population-specific reference values to eliminate the well-recognized influence of ethnic variation on lung function. This study was designed to derive spirometric prediction equations for healthy Omani adults. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow rate (PEFR), and forced expiratory flow at 25{\%} to 75{\%} of FVC (FEF25-75{\%}) were measured in 419 {"}healthy{"} nonsmoking Omani adults (256 men, 163 women), aged 18-65 years. Multiple linear regression analysis was performed for each spirometric parameter against age, height, and weight for men and women separately, and prediction equations for all the above parameters were derived and compared with values derived using equations published from other populations. All measured spirometric parameters increased with height and decreased with age, and they were all significantly higher in men. In contrast, FEV1/FVC{\%} values decreased with height and increased with age and were higher in women. The predicted normal values of FVC and FEV1 for our subjects using the derived equations were lower by 7-17{\%} compared with respective Caucasian values, with smaller difference in the predicted values of PEFR, FEV1/FVC{\%}, and FEF25-75{\%}. This report presents previously unavailable spirometric reference equations for the Omani adults. Our findings highlight the need to use reference values based on updated data derived from relevant populations.",
keywords = "Ethnic Arab, Lung function, Omani, Reference values, Spirometry",
author = "Al-Rawas, {Omar A.} and Sawasn Baddar and Al-Maniri, {Abdullah A.} and Jothi Balaji and B. Jayakrishnan and Al-Riyami, {Bazdawi M.}",
year = "2009",
month = "8",
doi = "10.1007/s00408-009-9148-4",
language = "English",
volume = "187",
pages = "245--251",
journal = "Lung",
issn = "0341-2040",
publisher = "Springer New York",
number = "4",

}

TY - JOUR

T1 - Normal spirometric reference values for omani adults

AU - Al-Rawas, Omar A.

AU - Baddar, Sawasn

AU - Al-Maniri, Abdullah A.

AU - Balaji, Jothi

AU - Jayakrishnan, B.

AU - Al-Riyami, Bazdawi M.

PY - 2009/8

Y1 - 2009/8

N2 - International guidelines recommend the use of population-specific reference values to eliminate the well-recognized influence of ethnic variation on lung function. This study was designed to derive spirometric prediction equations for healthy Omani adults. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow rate (PEFR), and forced expiratory flow at 25% to 75% of FVC (FEF25-75%) were measured in 419 "healthy" nonsmoking Omani adults (256 men, 163 women), aged 18-65 years. Multiple linear regression analysis was performed for each spirometric parameter against age, height, and weight for men and women separately, and prediction equations for all the above parameters were derived and compared with values derived using equations published from other populations. All measured spirometric parameters increased with height and decreased with age, and they were all significantly higher in men. In contrast, FEV1/FVC% values decreased with height and increased with age and were higher in women. The predicted normal values of FVC and FEV1 for our subjects using the derived equations were lower by 7-17% compared with respective Caucasian values, with smaller difference in the predicted values of PEFR, FEV1/FVC%, and FEF25-75%. This report presents previously unavailable spirometric reference equations for the Omani adults. Our findings highlight the need to use reference values based on updated data derived from relevant populations.

AB - International guidelines recommend the use of population-specific reference values to eliminate the well-recognized influence of ethnic variation on lung function. This study was designed to derive spirometric prediction equations for healthy Omani adults. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow rate (PEFR), and forced expiratory flow at 25% to 75% of FVC (FEF25-75%) were measured in 419 "healthy" nonsmoking Omani adults (256 men, 163 women), aged 18-65 years. Multiple linear regression analysis was performed for each spirometric parameter against age, height, and weight for men and women separately, and prediction equations for all the above parameters were derived and compared with values derived using equations published from other populations. All measured spirometric parameters increased with height and decreased with age, and they were all significantly higher in men. In contrast, FEV1/FVC% values decreased with height and increased with age and were higher in women. The predicted normal values of FVC and FEV1 for our subjects using the derived equations were lower by 7-17% compared with respective Caucasian values, with smaller difference in the predicted values of PEFR, FEV1/FVC%, and FEF25-75%. This report presents previously unavailable spirometric reference equations for the Omani adults. Our findings highlight the need to use reference values based on updated data derived from relevant populations.

KW - Ethnic Arab

KW - Lung function

KW - Omani

KW - Reference values

KW - Spirometry

UR - http://www.scopus.com/inward/record.url?scp=68349113796&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68349113796&partnerID=8YFLogxK

U2 - 10.1007/s00408-009-9148-4

DO - 10.1007/s00408-009-9148-4

M3 - Article

C2 - 19399552

AN - SCOPUS:68349113796

VL - 187

SP - 245

EP - 251

JO - Lung

JF - Lung

SN - 0341-2040

IS - 4

ER -