Nocardia asteroides peritoneal dialysis-related peritonitis: First case in pediatrics, treated with protracted linezolid

Mohamed El-Naggari; Ibtisam El Nour; Dana Al-Nabhani; Zakaria Al Muharrmi; Heba Gaafar; Anas A W Abdelmogheth

doi:10.1016/j.jiph.2015.11.003

Nocardia asteroides peritoneal dialysis-related peritonitis: First case in pediatrics, treated with protracted linezolid

Mohamed El-Naggari^*, Ibtisam El Nour, Dana Al-Nabhani, Zakaria Al Muharrmi, Heba Gaafar, Anas A W Abdelmogheth

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.

Original language	English
Pages (from-to)	192-197
Number of pages	6
Journal	Journal of Infection and Public Health
Volume	9
Issue number	2
DOIs	https://doi.org/10.1016/j.jiph.2015.11.003
Publication status	Published - Mar 1 2016

Keywords

Continuous ambulatory peritoneal dialysis
Intra-abdominal abscess
Nocardia asteroides
Oman
Peritoneal dialysis
Peritonitis

ASJC Scopus subject areas

Infectious Diseases
Public Health, Environmental and Occupational Health

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Nocardia asteroides peritoneal dialysis-related peritonitis : First case in pediatrics, treated with protracted linezolid. / El-Naggari, Mohamed ; El Nour, Ibtisam ; Al-Nabhani, Dana ; Al Muharrmi, Zakaria; Gaafar, Heba; Abdelmogheth, Anas A W.

In: Journal of Infection and Public Health, Vol. 9, No. 2, 01.03.2016, p. 192-197.

Research output: Contribution to journal › Article › peer-review

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abstract = "Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.",

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