Nocardia asteroides peritoneal dialysis-related peritonitis: First case in pediatrics, treated with protracted linezolid

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Abstract

Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.

Original languageEnglish
Pages (from-to)192-197
Number of pages6
JournalJournal of Infection and Public Health
Volume9
Issue number2
DOIs
Publication statusPublished - Mar 1 2016

Fingerprint

Linezolid
Nocardia asteroides
Peritoneal Dialysis
Peritonitis
Nocardia
Pediatrics
Abdominal Abscess
Sulfamethoxazole Drug Combination Trimethoprim
Case Management
Renal Dialysis
Hospitalization
Therapeutics
Growth

Keywords

  • Continuous ambulatory peritoneal dialysis
  • Intra-abdominal abscess
  • Nocardia asteroides
  • Oman
  • Peritoneal dialysis
  • Peritonitis

ASJC Scopus subject areas

  • Infectious Diseases
  • Public Health, Environmental and Occupational Health

Cite this

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title = "Nocardia asteroides peritoneal dialysis-related peritonitis: First case in pediatrics, treated with protracted linezolid",
abstract = "Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.",
keywords = "Continuous ambulatory peritoneal dialysis, Intra-abdominal abscess, Nocardia asteroides, Oman, Peritoneal dialysis, Peritonitis",
author = "Mohamed El-Naggari and {El Nour}, Ibtisam and Dana Al-Nabhani and {Al Muharrmi}, Zakaria and Heba Gaafar and Abdelmogheth, {Anas A W}",
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T2 - First case in pediatrics, treated with protracted linezolid

AU - El-Naggari, Mohamed

AU - El Nour, Ibtisam

AU - Al-Nabhani, Dana

AU - Al Muharrmi, Zakaria

AU - Gaafar, Heba

AU - Abdelmogheth, Anas A W

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N2 - Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.

AB - Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects.

KW - Continuous ambulatory peritoneal dialysis

KW - Intra-abdominal abscess

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KW - Oman

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KW - Peritonitis

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