Nasal NK/T cell lymphoma mimicking a squamous cell carcinoma: A case report

Manna Valiathan; Ravikala V. Rao; Lakshmi Rao; Elaine S. Jaffe; Suresh Pillai

Nasal NK/T cell lymphoma mimicking a squamous cell carcinoma: A case report

Manna Valiathan^*, Ravikala V. Rao, Lakshmi Rao, Elaine S. Jaffe, Suresh Pillai

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A 48 year old female presented with extensive ulceration of the nasal septum of 8 months duration. Investigations confirmed the local nature of the disease. A biopsy revealed large zones of ischemic necrosis and abnormal lymphoid cells invading vessel walls and glandular structures. Florid squamous metaplasia, and pseudoepitheliomatous hyperplasia of mucosal epithelium mimicked squamous cell carcinoma and necrotising sialometaplasia. Immunohistochemistry and insitu hybridization confirmed the diagnosis of an EBV positive, Nasal NK/T cell lymphoma. A Pubmed/Medline search suggests that this is the first documented case from India.

Original language	English
Pages (from-to)	257-259
Number of pages	3
Journal	Indian Journal of Pathology and Microbiology
Volume	48
Issue number	2
Publication status	Published - 2005
Externally published	Yes

Keywords

Angiocentric
Lymphoma
NK/T cell
Nasal

ASJC Scopus subject areas

Pathology and Forensic Medicine
Microbiology (medical)

Cite this

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title = "Nasal NK/T cell lymphoma mimicking a squamous cell carcinoma: A case report",

abstract = "A 48 year old female presented with extensive ulceration of the nasal septum of 8 months duration. Investigations confirmed the local nature of the disease. A biopsy revealed large zones of ischemic necrosis and abnormal lymphoid cells invading vessel walls and glandular structures. Florid squamous metaplasia, and pseudoepitheliomatous hyperplasia of mucosal epithelium mimicked squamous cell carcinoma and necrotising sialometaplasia. Immunohistochemistry and insitu hybridization confirmed the diagnosis of an EBV positive, Nasal NK/T cell lymphoma. A Pubmed/Medline search suggests that this is the first documented case from India.",

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T2 - A case report

AU - Valiathan, Manna

AU - Rao, Ravikala V.

AU - Rao, Lakshmi

AU - Jaffe, Elaine S.

AU - Pillai, Suresh

PY - 2005

Y1 - 2005

N2 - A 48 year old female presented with extensive ulceration of the nasal septum of 8 months duration. Investigations confirmed the local nature of the disease. A biopsy revealed large zones of ischemic necrosis and abnormal lymphoid cells invading vessel walls and glandular structures. Florid squamous metaplasia, and pseudoepitheliomatous hyperplasia of mucosal epithelium mimicked squamous cell carcinoma and necrotising sialometaplasia. Immunohistochemistry and insitu hybridization confirmed the diagnosis of an EBV positive, Nasal NK/T cell lymphoma. A Pubmed/Medline search suggests that this is the first documented case from India.

AB - A 48 year old female presented with extensive ulceration of the nasal septum of 8 months duration. Investigations confirmed the local nature of the disease. A biopsy revealed large zones of ischemic necrosis and abnormal lymphoid cells invading vessel walls and glandular structures. Florid squamous metaplasia, and pseudoepitheliomatous hyperplasia of mucosal epithelium mimicked squamous cell carcinoma and necrotising sialometaplasia. Immunohistochemistry and insitu hybridization confirmed the diagnosis of an EBV positive, Nasal NK/T cell lymphoma. A Pubmed/Medline search suggests that this is the first documented case from India.

KW - Angiocentric

KW - Lymphoma

KW - NK/T cell

KW - Nasal

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JO - Indian Journal of Pathology and Microbiology

JF - Indian Journal of Pathology and Microbiology

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ER -

Nasal NK/T cell lymphoma mimicking a squamous cell carcinoma: A case report

Abstract

Keywords

ASJC Scopus subject areas

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