Abstract
The title compound, N-(2-hydroxy-1,1-dimethylethyl)-3-methylbenzamide was synthesized by reacting 3-methylbenzoyl chloride or 3-methylbenzoic acid with 2-amino-2-methyl-1-propanol. In the present report, the synthesized target compound was fully characterized by various spectroscopic methods (1H NMR,13C NMR, IR, GC-MS), its composition confirmed by elemental analysis, and its structure determined and confirmed by X-ray analysis. The importance of this compound lies in its possession of an N,O-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C–H bond functionalization reactions.
Original language | English |
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Article number | M1099 |
Journal | MolBank |
Volume | 2020 |
Issue number | 1 |
DOIs | |
Publication status | Published - Mar 2020 |
Keywords
- Benzamides
- Bidentate directing groups
- Bis-chelates
- C
- Chelation assistance
- H bond functionalization
- Organic synthesis
- X-ray structure determination
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry