N-(2-hydroxy-1,1-dimethylethyl)-3-methylbenzamide

Hamad H. Al Mamari*, Yousuf Al Lawati

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The title compound, N-(2-hydroxy-1,1-dimethylethyl)-3-methylbenzamide was synthesized by reacting 3-methylbenzoyl chloride or 3-methylbenzoic acid with 2-amino-2-methyl-1-propanol. In the present report, the synthesized target compound was fully characterized by various spectroscopic methods (1H NMR,13C NMR, IR, GC-MS), its composition confirmed by elemental analysis, and its structure determined and confirmed by X-ray analysis. The importance of this compound lies in its possession of an N,O-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C–H bond functionalization reactions.

Original languageEnglish
Article numberM1099
JournalMolBank
Volume2020
Issue number1
DOIs
Publication statusPublished - Mar 2020
Externally publishedYes

Keywords

  • Benzamides
  • Bidentate directing groups
  • Bis-chelates
  • C
  • Chelation assistance
  • H bond functionalization
  • Organic synthesis
  • X-ray structure determination

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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