Myelomatous pleural effusion: Case report and review of the literature

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Abstract

Plasma cell myeloma is an uncommon disease which, besides primarily involving the bone marrow, has a tendency to involve other organs thus presenting with different clinical manifestations. While pleural effusions are infrequent in this disease, true myelomatous pleural effusions are extremely rare. We report the case of a middle-aged Omani man with relapsed plasma cell myeloma who developed bilateral pleural effusions. The diagnosis of myelomatous pleural effusion was made by finding many abnormal plasma cells as well as a high level of a monoclonal protein (IgG κ) in the pleural fluid. In spite of a good initial response to therapy, the patient had progressive disease and died 6 months later with bacterial sepsis. We present a review of the literature that indicates the rarity of such a manifestation and its association with poor prognosis and short survival.

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalSultan Qaboos University Medical Journal
Volume11
Issue number2
Publication statusPublished - May 2011

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Keywords

  • Case report
  • Multiple myeloma
  • Oman
  • Plasma cells
  • Pleural effusion

ASJC Scopus subject areas

  • Medicine(all)

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