Mixed Connective Tissue Disease with Severe Axonal Polyneuropathy: A Case Report

Talal Al Lawati; Batool Hassan

doi:10.5001/omj.2022.08

Mixed Connective Tissue Disease with Severe Axonal Polyneuropathy: A Case Report

Talal Al Lawati^*, Batool Hassan

^*Corresponding author for this work

Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Mixed connective tissue disease (MCTD) is a unique disorder characterized by the presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of various connective tissue disorders including systemic lupus erythematosus, scleroderma, and myositis. Severe renal or neurological involvement is unusual with this disorder. We describe a case of biopsy-confirmed severe sensorimotor axonal polyneuropathy in a middle-aged gentleman as his first presentation for MCTD.

Original language	English
Article number	e376
Journal	Oman Medical Journal
Volume	37
Issue number	3
DOIs	https://doi.org/10.5001/omj.2022.08
Publication status	Published - May 2022

Keywords

Mixed Connective Tissue Disease
Polyneuropathies
Pulmonary Arterial Hypertension

ASJC Scopus subject areas

Medicine(all)

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10.5001/omj.2022.08

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abstract = "Mixed connective tissue disease (MCTD) is a unique disorder characterized by the presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of various connective tissue disorders including systemic lupus erythematosus, scleroderma, and myositis. Severe renal or neurological involvement is unusual with this disorder. We describe a case of biopsy-confirmed severe sensorimotor axonal polyneuropathy in a middle-aged gentleman as his first presentation for MCTD.",

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AB - Mixed connective tissue disease (MCTD) is a unique disorder characterized by the presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of various connective tissue disorders including systemic lupus erythematosus, scleroderma, and myositis. Severe renal or neurological involvement is unusual with this disorder. We describe a case of biopsy-confirmed severe sensorimotor axonal polyneuropathy in a middle-aged gentleman as his first presentation for MCTD.

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KW - Polyneuropathies

KW - Pulmonary Arterial Hypertension

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Mixed Connective Tissue Disease with Severe Axonal Polyneuropathy: A Case Report

Abstract

Keywords

ASJC Scopus subject areas

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