Misdiagnosis of myasthenia gravis and subsequent clinical implication: A case report and review of literature

Abdullah Al-Asmi, Ramachandiran Nandhagopal*, P. C. Jacob, Arunodaya Gujjar

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


The autoimmune disease, myasthenia gravis (MG), can mimic a variety of neurological disorders leading to a delay in diagnosis and treatment. On occasions, misdiagnosis of MG could lead to unnecessary and potentially harmful therapeutic interventions. We report on a 12 year-old boy, in whom MG was mistaken for meningitic sequelae and subsequently for critical neuropathy/myopathy resulting in considerable morbidity for nearly a decade. Subsequent correct diagnosis and optimal management resulted in significant improvement in his functional status. We discuss the importance of considering MG as one of the potential differential diagnoses among cases of recurrent respiratory pump failure, or unexplained bulbar symptoms where documentary proof of the previous diagnoses including work-up for MG is lacking. We also review the literature on MG misdiagnosis and highlight the potential pitfalls in MG diagnosis.

Original languageEnglish
Pages (from-to)654-659
Number of pages6
JournalSultan Qaboos University Medical Journal
Issue number1
Publication statusPublished - Feb 2012
Externally publishedYes


  • Bulbar palsy
  • Case report
  • Meningitis
  • Myasthenia gravis
  • Oman
  • Pneumonia
  • Sequelae

ASJC Scopus subject areas

  • Medicine(all)


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