TY - JOUR
T1 - Microwave-assisted palladium-catalyzed cross-coupling reactions
T2 - Generation of carbon–carbon bond
AU - Salih, Kifah S.M.
AU - Baqi, Younis
N1 - Funding Information:
This work was supported by Arab-German Young Academy of Sciences and Humanities (AGYA) grants (TP_2018_29 & TP_2019_04).
Funding Information:
Funding: This work was supported by Arab-German Young Academy of Sciences and Humanities (AGYA) grants (TP_2018_29 & TP_2019_04).
Funding Information:
Acknowledgments: The publication of this article was funded by the Qatar National Library.
Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2020/1
Y1 - 2020/1
N2 - Cross-coupling reactions furnishing carbon–carbon (C–C) bond is one of the most challenging tasks in organic syntheses. The early developed reaction protocols by Negishi, Heck, Kumada, Sonogashira, Stille, Suzuki, and Hiyama, utilizing palladium or its salts as catalysis have, for decades, attracted and inspired researchers affiliated with academia and industry. Tremendous efforts have been paid to develop and achieve more sustainable reaction conditions, such as the reduction in energy consumption by applying the microwave irradiation technique. Chemical reactions under controlled microwave conditions dramatically reduce the reaction time and therefore resulting in increase in the yield of the desired product by minimizing the formation of side products. In this review, we mainly focus on the recent advances and applications of palladium catalyzed cross-coupling carbon–carbon bond formation under microwave technology.
AB - Cross-coupling reactions furnishing carbon–carbon (C–C) bond is one of the most challenging tasks in organic syntheses. The early developed reaction protocols by Negishi, Heck, Kumada, Sonogashira, Stille, Suzuki, and Hiyama, utilizing palladium or its salts as catalysis have, for decades, attracted and inspired researchers affiliated with academia and industry. Tremendous efforts have been paid to develop and achieve more sustainable reaction conditions, such as the reduction in energy consumption by applying the microwave irradiation technique. Chemical reactions under controlled microwave conditions dramatically reduce the reaction time and therefore resulting in increase in the yield of the desired product by minimizing the formation of side products. In this review, we mainly focus on the recent advances and applications of palladium catalyzed cross-coupling carbon–carbon bond formation under microwave technology.
KW - C-C bond formation
KW - Cross-coupling reaction
KW - Microwave
KW - Pd catalysts
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U2 - 10.3390/catal10010004
DO - 10.3390/catal10010004
M3 - Review article
AN - SCOPUS:85077201193
SN - 2073-4344
VL - 10
JO - Catalysts
JF - Catalysts
IS - 1
M1 - 4
ER -