Lymphocytic infundibulo-neurohypophysitis: An unusual cause of recurrent optic neuropathy in a child

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Abstract

Lymphocytic infundibulo-neurohypophysitis (LINH), a rare autoimmune disease, is distinct from lymphocytic hypophysitis and is characterized by lymphocytic and plasma cell infiltration of the posterior lobe of the pituitary and the pituitary stalk.1 We report the case of a young boy who presented with recurrent, steroid-responsive optic nerve dysfunction and diabetes insipidus. T1-weighted magnetic resonance imaging scans of the brain showed an isointense soft tissue mass within the sella turcica and a thickened pituitary stalk. Tissue specimen resected at transsphenoidal surgery revealed chronic inflammation with infiltration of lymphocytes and no granulomatosis or necrosis, establishing the diagnosis of LINH.2 This is the first report of optic neuropathy in association with LINH in a child.

Original languageEnglish
Pages (from-to)207-209
Number of pages3
JournalJournal of AAPOS
Volume13
Issue number2
DOIs
Publication statusPublished - Apr 2009

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ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

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