Low folate and vitamin B12 nourishment is common in Omani children with newly diagnosed autism

Yahya M. Al-Farsi, Mostafa I. Waly, Richard C. Deth, Marwan M. Al-Sharbati, Mohamed Al-Shafaee, Omar Al-Farsi, Maha M. Al-Khaduri, Ishita Gupta, Amanat Ali, Maha Al-Khalili, Samir Al-Adawi, Nathaniel W. Hodgson, Allal Ouhtit*

*Corresponding author for this work

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Objective: Arab populations lack data related to nutritional assessment in children with autism spectrum disorders (ASDs), especially micronutrient deficiencies such as folate and vitamin B12. Methods: To assess the dietary and serum folate and vitamin B12 statuses, a hospital-based case-control study was conducted in 80 Omani children (40 children with ASDs versus 40 controls). Results: The ASD cases showed significantly lower levels of folate, vitamin B12, and related parameters in dietary intake and serum levels. Conclusion: These data showed that Omani children with ASDs exhibit significant deficiencies in folate and vitamin B12 and call for increasing efforts to ensure sufficient intakes of essential nutrients by children with ASDs to minimize or reverse any ongoing impact of nutrient deficiencies.

Original languageEnglish
Pages (from-to)537-541
Number of pages5
JournalNutrition
Volume29
Issue number3
DOIs
Publication statusPublished - Mar 2013

Keywords

  • Autism
  • Folate
  • Methylation
  • Nutrition
  • Oman
  • Vitamin B12

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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