Leprous neuromyositis: A rare clinical entity and review of the literature

Shubhanker Mitra, Karthik Gunasekaran, Geeta Chacko, Samuel George Hansdak

Research output: Contribution to journalArticle

Abstract

Mycobacterium leprae, the causative agent of leprosy (Hansen's disease), is a slow growing intracellular acid-fast bacillus that affects the skin, peripheral nerves and respiratory tract. In patients with suppressed cell-mediated immunity, the infiltration of the Bacilli can produce disseminated illness such as leprous neuromyositis. We reported a case of 56-year-old gentleman presenting with pyrexia of unknown origin, asymmetric sensory motor axonal polyneuropathy and was on chronic exogenous steroid therapy. On evaluation, his skin, muscle, nerve and bone marrow biopsy showed numerous globi of acid-fast Bacilli suggestive of leprous neuromyositis, a rare form of disseminated Hansen's disease. We reported this case in view of its rarity, atypical manifestation of a relatively rare disease and literature review on poor electrophysiological correlation in the diagnosis of leprous neuromyositis as compared to the histopathological examination.

Original languageEnglish
Pages (from-to)95-97
Number of pages3
JournalIndian Journal of Medical Microbiology
Volume34
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Leprosy
Bacillus
Mycobacterium leprae
Skin
Acids
Polyneuropathies
Rare Diseases
Peripheral Nerves
Cellular Immunity
Respiratory System
Fever
Bone Marrow
Steroids
Biopsy
Muscles
Therapeutics

Keywords

  • Chronic inflammatory demyelinating polyneuropathy
  • chronic sensory motor polyradiculoneuropathy
  • leprous neuromyositis

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Leprous neuromyositis : A rare clinical entity and review of the literature. / Mitra, Shubhanker; Gunasekaran, Karthik; Chacko, Geeta; Hansdak, Samuel George.

In: Indian Journal of Medical Microbiology, Vol. 34, No. 1, 01.01.2016, p. 95-97.

Research output: Contribution to journalArticle

Mitra, Shubhanker ; Gunasekaran, Karthik ; Chacko, Geeta ; Hansdak, Samuel George. / Leprous neuromyositis : A rare clinical entity and review of the literature. In: Indian Journal of Medical Microbiology. 2016 ; Vol. 34, No. 1. pp. 95-97.
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