Larvicidal activity of extracts and triterpenoids from Lantana camara

Majekodunmi O. Fatope; Labaran Salihu; Stephen K. Asante; Yoshio Takeda

doi:10.1076/phbi.40.8.564.14654

Larvicidal activity of extracts and triterpenoids from Lantana camara

Majekodunmi O. Fatope^*, Labaran Salihu, Stephen K. Asante, Yoshio Takeda

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Extracts of the leaves, twigs, stems and roots of Lantana camara Linn. (Verbenaceae) were solvent-partitioned and screened for activity in the brine shrimp lethality test (BST). The active fractions yielded known oleanonic acid (1), lantadene A (2) and oleanolic acid (3), which were very toxic to brine shrimp larvae. Compounds 1-3 were not lethal to Spodoptera littoralis Biosduval (Lepidoptera: Noctuidae), Clavigralla tomentosicollis Stal. (Hemiptera: Coreidae) and Aphis craccivora Koch (Homoptera: Aphididae) when tested at 5000 μg/ml. Compound 2, however, suppressed the fecundity of C. tomentosicollis at this concentration.

Original language	English
Pages (from-to)	564-567
Number of pages	4
Journal	Pharmaceutical Biology
Volume	40
Issue number	8
DOIs	https://doi.org/10.1076/phbi.40.8.564.14654
Publication status	Published - Dec 2002

Keywords

Brine shrimp
Lantana camara
Pest control
Triterpenes
Verbenaceae

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine

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10.1076/phbi.40.8.564.14654

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title = "Larvicidal activity of extracts and triterpenoids from Lantana camara",

abstract = "Extracts of the leaves, twigs, stems and roots of Lantana camara Linn. (Verbenaceae) were solvent-partitioned and screened for activity in the brine shrimp lethality test (BST). The active fractions yielded known oleanonic acid (1), lantadene A (2) and oleanolic acid (3), which were very toxic to brine shrimp larvae. Compounds 1-3 were not lethal to Spodoptera littoralis Biosduval (Lepidoptera: Noctuidae), Clavigralla tomentosicollis Stal. (Hemiptera: Coreidae) and Aphis craccivora Koch (Homoptera: Aphididae) when tested at 5000 μg/ml. Compound 2, however, suppressed the fecundity of C. tomentosicollis at this concentration.",

keywords = "Brine shrimp, Lantana camara, Pest control, Triterpenes, Verbenaceae",

author = "Fatope, {Majekodunmi O.} and Labaran Salihu and Asante, {Stephen K.} and Yoshio Takeda",

note = "Funding Information: This project was supported by grant F/2018-2F from the International Foundation for Science to MOF and valuable research resources from the College of Science, Sultan Qaboos University, Sultanate of Oman. One of us, SL, is grateful to NDA for a study fellowship.",

year = "2002",

month = dec,

doi = "10.1076/phbi.40.8.564.14654",

language = "English",

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AU - Fatope, Majekodunmi O.

AU - Salihu, Labaran

AU - Asante, Stephen K.

AU - Takeda, Yoshio

N1 - Funding Information: This project was supported by grant F/2018-2F from the International Foundation for Science to MOF and valuable research resources from the College of Science, Sultan Qaboos University, Sultanate of Oman. One of us, SL, is grateful to NDA for a study fellowship.

PY - 2002/12

Y1 - 2002/12

N2 - Extracts of the leaves, twigs, stems and roots of Lantana camara Linn. (Verbenaceae) were solvent-partitioned and screened for activity in the brine shrimp lethality test (BST). The active fractions yielded known oleanonic acid (1), lantadene A (2) and oleanolic acid (3), which were very toxic to brine shrimp larvae. Compounds 1-3 were not lethal to Spodoptera littoralis Biosduval (Lepidoptera: Noctuidae), Clavigralla tomentosicollis Stal. (Hemiptera: Coreidae) and Aphis craccivora Koch (Homoptera: Aphididae) when tested at 5000 μg/ml. Compound 2, however, suppressed the fecundity of C. tomentosicollis at this concentration.

AB - Extracts of the leaves, twigs, stems and roots of Lantana camara Linn. (Verbenaceae) were solvent-partitioned and screened for activity in the brine shrimp lethality test (BST). The active fractions yielded known oleanonic acid (1), lantadene A (2) and oleanolic acid (3), which were very toxic to brine shrimp larvae. Compounds 1-3 were not lethal to Spodoptera littoralis Biosduval (Lepidoptera: Noctuidae), Clavigralla tomentosicollis Stal. (Hemiptera: Coreidae) and Aphis craccivora Koch (Homoptera: Aphididae) when tested at 5000 μg/ml. Compound 2, however, suppressed the fecundity of C. tomentosicollis at this concentration.

KW - Brine shrimp

KW - Lantana camara

KW - Pest control

KW - Triterpenes

KW - Verbenaceae

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EP - 567

JO - Pharmaceutical Biology

JF - Pharmaceutical Biology

IS - 8

ER -

Larvicidal activity of extracts and triterpenoids from Lantana camara

Abstract

Keywords

ASJC Scopus subject areas

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