KMT2A-MLLT3 AML masquerading as JMML may disguise fatal leukemia

Ashraf Abdullah Saad*, Ismail El Beshlawi, Mathew Zachariah, Yasser Wali

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We present a mortality case showcasing t(9;11)-positive acute myeloid leukemia/juvenile myelomonocytic leukemia (AML/JMML) overlap to shed light on this lethal molecular subtype of AML. In this case, the flawed assumption that JMML was to blame impeded the prompt undertaking of appropriate treatment for AML in our 14-month-old patient. This article aims to scrutinize the catastrophic sequel of such an overlap in leukemia and refutes the contemporary diagnostic methods.

Original languageEnglish
Pages (from-to)553-555
Number of pages3
JournalOman Medical Journal
Volume34
Issue number6
DOIs
Publication statusPublished - Nov 2019

Keywords

  • Acute Myeloid Leukemia
  • Histone-Lysine N-Methyltransferase 2A
  • Juvenile Myelomonocytic Leukemia

ASJC Scopus subject areas

  • Medicine(all)

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