Isolated ipsilateral nipple recurrence: Important lessons to learn

Shahrun Niza Abdullah Suhami, Rohaizak Muhammad*, Ibrahim Naqiyah, Srijit Das, Noraidah Masir

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Most breast cancer recurrences occur in the surgical scars or within other quadrants of the same breast. Isolated tumour recurrence occurring in the nipple after breast-conserving surgery and radiotherapy is extremely unusual. The reason for this is unknown, but is speculated to be due to involved surgical margins or an occult involvement of the nipple-areolar complex in a breast cancer of the same breast. We present a case of a 44-year-old Indian woman who had recurrent tumour over her right nipple after an ipsilateral breast-conserving surgery that was followed by adjuvant chemotherapy and radiotherapy. There was no typical malignancy features from the mammogram. However, histopathological study confirmed a malignant growth that infiltrated into the dermis and the underneath breast tissue. Completion mastectomy was then performed and the patient was later treated with Taxane-based chemotherapy. Nipple recurrence after breast-conserving surgery and adjuvant radiotherapy may be confused with other nipple conditions such as Paget's disease of the breast. Comprehensive assessments, which include mammogram and biopsy, have proved that such recurrence do occur, as presented in this case. This warrants a specific management strategy.

Original languageEnglish
Pages (from-to)84-86
Number of pages3
JournalMalaysian Journal of Medical Sciences
Volume18
Issue number2
Publication statusPublished - Apr 2011
Externally publishedYes

Keywords

  • Breast-conserving surgery
  • Diagnosis
  • Nipple
  • Recurrence
  • Surgical oncology

ASJC Scopus subject areas

  • Medicine(all)

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