TY - JOUR
T1 - Introduction to Systematic Reviews and Meta-analyses of Therapeutic Studies
AU - Al-Khabori, Murtadha
AU - Rasool, Wasif
N1 - Publisher Copyright:
© 2022, Oman Medical Specialty Board. All rights reserved.
PY - 2021/9/30
Y1 - 2021/9/30
N2 - A systematic review is a specific and reproducible method to search, identify, select, appraise, and summarize all studies relevant to a particular health care question. In this paper, we will review the concept of level of evidence, define the terms systematic review and meta-analysis, and outline the steps in performing a systematic review and meta-analysis with an illustrative example. We will also introduce some important concepts in systematic reviews and meta-analyses like heterogeneity, publication bias, forest plots, and quality assessment. Finally, this review will focus on systematic reviews addressing therapeutic research questions.
AB - A systematic review is a specific and reproducible method to search, identify, select, appraise, and summarize all studies relevant to a particular health care question. In this paper, we will review the concept of level of evidence, define the terms systematic review and meta-analysis, and outline the steps in performing a systematic review and meta-analysis with an illustrative example. We will also introduce some important concepts in systematic reviews and meta-analyses like heterogeneity, publication bias, forest plots, and quality assessment. Finally, this review will focus on systematic reviews addressing therapeutic research questions.
KW - Clinical Trial
KW - Meta-Analysis
KW - Systematic Review
UR - http://www.scopus.com/inward/record.url?scp=85139794763&partnerID=8YFLogxK
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U2 - 10.5001/omj.2022.42
DO - 10.5001/omj.2022.42
M3 - Article
C2 - 36263198
SN - 1999-768X
VL - 37
JO - Oman Medical Journal
JF - Oman Medical Journal
IS - 5
M1 - e428
ER -