Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children

P. Venugopalan; A. K. Agarwal; F. O. Akinbami; I. B. El Nour; R. Subramanyan

doi:10.1016/S0167-5273(98)00084-9

Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children

P. Venugopalan, A. K. Agarwal^*, F. O. Akinbami, I. B. El Nour, R. Subramanyan

^*Corresponding author for this work

Child Health

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	International Journal of Cardiology
Volume	65
Issue number	2
DOIs	https://doi.org/10.1016/S0167-5273(98)00084-9
Publication status	Published - Jul 1 1998

Keywords

Dilated cardiomyopathy
Dobutamine infusion
Prognosis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/S0167-5273(98)00084-9

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title = "Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children",

abstract = "We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.",

keywords = "Dilated cardiomyopathy, Dobutamine infusion, Prognosis",

author = "P. Venugopalan and Agarwal, {A. K.} and Akinbami, {F. O.} and {El Nour}, {I. B.} and R. Subramanyan",

note = "Funding Information: We gratefully acknowledge the help of Prof. A. Saha and Dr. K.R. Sundaram of the Department of Epidemiology and Medical Statistics, in the statistical analysis of the data. ",

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AU - Agarwal, A. K.

AU - Akinbami, F. O.

AU - El Nour, I. B.

AU - Subramanyan, R.

N1 - Funding Information: We gratefully acknowledge the help of Prof. A. Saha and Dr. K.R. Sundaram of the Department of Epidemiology and Medical Statistics, in the statistical analysis of the data.

PY - 1998/7/1

Y1 - 1998/7/1

N2 - We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.

AB - We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.

KW - Dilated cardiomyopathy

KW - Dobutamine infusion

KW - Prognosis

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Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children

Abstract

Keywords

ASJC Scopus subject areas

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