Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children

P. Venugopalan; A. K. Agarwal; F. O. Akinbami; I. B. El Nour; R. Subramanyan

doi:10.1016/S0167-5273(98)00084-9

Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children

P. Venugopalan, A. K. Agarwal^*, F. O. Akinbami, I. B. El Nour, R. Subramanyan

^*Corresponding author for this work

Child Health

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	International Journal of Cardiology
Volume	65
Issue number	2
DOIs	https://doi.org/10.1016/S0167-5273(98)00084-9
Publication status	Published - Jul 1 1998

Keywords

Dilated cardiomyopathy
Dobutamine infusion
Prognosis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Improved prognosis of heart failure due to idiopathic dilated cardiomyopathy in children",

abstract = "We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.",

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N2 - We analyzed the outcome of 18 children with idiopathic dilated cardiomyopathy (IDC). There was a striking female preponderance (M:F = 1:3.5) and 15 (83%) presented below the age of 2 years. Follow up for a mean duration of 3.5 years revealed complete recovery in seven (43%) and an additional three (19%) became asymptomatic. Three (19%) died and another three (19%) continued to be symptomatic but in controlled heart failure. Two were lost to follow up. Among those who improved, the majority (75%) did so in 1.5 years. Three of five patients who received periodic dobutamine infusion showed improvement in quality of life. The survivals of 94% at 1 year and 87% at 3 years are significantly better than those previously reported. This is the first such study of IDC in children from the Arab peninsula.

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