Impact of anemia on in-hospital, one-month and one-year mortality in patients with acute coronary syndrome from the Middle East

Kadhim Sulaiman*, Panduranga Prashanth, Ibrahim Al-Zakwani, Wael Al-Mahmeed, Ahmed Al-Motarreb, Jassim Al Suwaidi, Haitham Amin, Nidal Asaad, Ahmad Hersi, Hussam A. Al Faleh, Shukri A. Al Saif, Alawi A. Alsheikh-Ali, Jawad Al Lawati, Khalid Al-Habib

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Aim: The aim of this study was to evaluate the impact of admission anemia on in-hospital, one-month, and one-year mortality in patients from the Middle East with acute coronary syndrome (ACS). Methods: Data were analyzed from 7922 consecutive patients admitted to hospitals throughout six Middle-Eastern countries with the final diagnosis of ACS, as part of Gulf RACE II (Registry of Acute Coronary Events II). Anemia at admission was defined according to the World Health Organization definition (<13 g/dL in men and <12 g/dL in women). Analyses were conducted using univariate and multivariate statistical techniques. Results: The median age of the cohort was 56 (48-65) years, with the majority being male (79%). Anemia at admission was present in 2241 patients (28%). Patients with anemia were more likely to have in-hospital complications including heart failure, recurrent ischemia, re-infarction, cardiogenic shock, stroke, and major bleed. Even after adjustment, anemia was still associated with mortality at in-hospital (odds ratio [OR]=1.71, 95% confidence interval [CI], 1.34-2.17; P<0.001), at one-month (OR=1.34, 95% CI, 1.06-1.71; P=0.016), and at one-year (OR=1.22, 95% CI, 1.01-1.49; P=0.049) post- admission with ACS. Conclusions: Admission anemia in patients with ACS from six Middle-Eastern countries was strongly associated with mortality at in-hospital, one-month, and at one-year. Hence, admission anemia must be considered in the initial risk assessment of ACS patients along with other risk scores.

Original languageEnglish
Pages (from-to)65-71
Number of pages7
JournalClinical Medicine and Research
Volume10
Issue number2
DOIs
Publication statusPublished - May 1 2012
Externally publishedYes

Keywords

  • Acute coronary syndrome
  • Anemia
  • Hemoglobin
  • Middle East
  • Mortality

ASJC Scopus subject areas

  • Community and Home Care

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