Idiopathic intracranial hypertension in Omani children

Amna Al-Futaisi, Raghad Abdwani, Mahmoud Fathalla, Ibrahim Al Zakwani, Hashem Javad, Sana Al-Zuhaibi, Anuradha Ganesh, Roshan Koul

Research output: Contribution to journalArticle

Abstract

Idiopathic intracranial hypertension (IIH) is a relatively rare disease in children. It is defined as raised intracranial pressure in the absence of clinical, laboratory or radiological evidence of an intracranial space occupying lesion. We aimed to evaluate the clinical and therapeutic features of IIH in a presenting group of Omani pediatric population. We conducted a retrospective chart review of patients below 18 years of age diagnosed with IIH between 1992 and 2006 according to Dandy's Modified Criteria at Sultan Qaboos University Hospital, Oman. Statistical analyses were conducted using McNemar's test. Nineteen patients were included in the study, 11 (58%) were males and 8 (42%) were females, with a ratio of 1.4:1. The median age at presentation was 8.5 years. The average body mass index of the patients was 18.1 with only 2 (11%) children being obese, both males and pubertal. All the patients except 1 (5%) were symptomatic at presentation. The commonest symptom was headache found in 16 (84%) patients. This was followed by visual symptoms in half of them in the form of diplopia (16%) or transient visual obscuration (37%). All patients had bilateral papilledema, 7 (37%) had visual field defects, 4 (21%) had an enlarged blind spot and 3 (17%) had restricted visual field. Secondary causes of intracranial hypertension were not identified but the associated conditions were sickle cell disease, Behcet disease, neurofibromatosis type 1, varicella infection, and brucellosis. Seventeen (89%) patients showed good response to treatment with acetazolamide, steroids or both, with resolution of symptoms and signs (p

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalJournal of Pediatric Neurology
Volume6
Issue number1
Publication statusPublished - 2008

Fingerprint

Pseudotumor Cerebri
Visual Fields
Oman
Papilledema
Acetazolamide
Neurofibromatosis 1
Intracranial Hypertension
Diplopia
Brucellosis
Chickenpox
Behcet Syndrome
Optic Disk
Intracranial Pressure
Sickle Cell Anemia
Rare Diseases
Signs and Symptoms
Headache
Body Mass Index
Steroids
Pediatrics

Keywords

  • Headache
  • Idiopathic intracranial hypertension
  • Papilledema

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Idiopathic intracranial hypertension in Omani children. / Al-Futaisi, Amna; Abdwani, Raghad; Fathalla, Mahmoud; Al Zakwani, Ibrahim; Javad, Hashem; Al-Zuhaibi, Sana; Ganesh, Anuradha; Koul, Roshan.

In: Journal of Pediatric Neurology, Vol. 6, No. 1, 2008, p. 35-38.

Research output: Contribution to journalArticle

@article{01decaaa1c224f60a8e2597e0df4420e,
title = "Idiopathic intracranial hypertension in Omani children",
abstract = "Idiopathic intracranial hypertension (IIH) is a relatively rare disease in children. It is defined as raised intracranial pressure in the absence of clinical, laboratory or radiological evidence of an intracranial space occupying lesion. We aimed to evaluate the clinical and therapeutic features of IIH in a presenting group of Omani pediatric population. We conducted a retrospective chart review of patients below 18 years of age diagnosed with IIH between 1992 and 2006 according to Dandy's Modified Criteria at Sultan Qaboos University Hospital, Oman. Statistical analyses were conducted using McNemar's test. Nineteen patients were included in the study, 11 (58{\%}) were males and 8 (42{\%}) were females, with a ratio of 1.4:1. The median age at presentation was 8.5 years. The average body mass index of the patients was 18.1 with only 2 (11{\%}) children being obese, both males and pubertal. All the patients except 1 (5{\%}) were symptomatic at presentation. The commonest symptom was headache found in 16 (84{\%}) patients. This was followed by visual symptoms in half of them in the form of diplopia (16{\%}) or transient visual obscuration (37{\%}). All patients had bilateral papilledema, 7 (37{\%}) had visual field defects, 4 (21{\%}) had an enlarged blind spot and 3 (17{\%}) had restricted visual field. Secondary causes of intracranial hypertension were not identified but the associated conditions were sickle cell disease, Behcet disease, neurofibromatosis type 1, varicella infection, and brucellosis. Seventeen (89{\%}) patients showed good response to treatment with acetazolamide, steroids or both, with resolution of symptoms and signs (p",
keywords = "Headache, Idiopathic intracranial hypertension, Papilledema",
author = "Amna Al-Futaisi and Raghad Abdwani and Mahmoud Fathalla and {Al Zakwani}, Ibrahim and Hashem Javad and Sana Al-Zuhaibi and Anuradha Ganesh and Roshan Koul",
year = "2008",
language = "English",
volume = "6",
pages = "35--38",
journal = "Journal of Pediatric Neuroradiology",
issn = "1304-2580",
publisher = "IOS Press",
number = "1",

}

TY - JOUR

T1 - Idiopathic intracranial hypertension in Omani children

AU - Al-Futaisi, Amna

AU - Abdwani, Raghad

AU - Fathalla, Mahmoud

AU - Al Zakwani, Ibrahim

AU - Javad, Hashem

AU - Al-Zuhaibi, Sana

AU - Ganesh, Anuradha

AU - Koul, Roshan

PY - 2008

Y1 - 2008

N2 - Idiopathic intracranial hypertension (IIH) is a relatively rare disease in children. It is defined as raised intracranial pressure in the absence of clinical, laboratory or radiological evidence of an intracranial space occupying lesion. We aimed to evaluate the clinical and therapeutic features of IIH in a presenting group of Omani pediatric population. We conducted a retrospective chart review of patients below 18 years of age diagnosed with IIH between 1992 and 2006 according to Dandy's Modified Criteria at Sultan Qaboos University Hospital, Oman. Statistical analyses were conducted using McNemar's test. Nineteen patients were included in the study, 11 (58%) were males and 8 (42%) were females, with a ratio of 1.4:1. The median age at presentation was 8.5 years. The average body mass index of the patients was 18.1 with only 2 (11%) children being obese, both males and pubertal. All the patients except 1 (5%) were symptomatic at presentation. The commonest symptom was headache found in 16 (84%) patients. This was followed by visual symptoms in half of them in the form of diplopia (16%) or transient visual obscuration (37%). All patients had bilateral papilledema, 7 (37%) had visual field defects, 4 (21%) had an enlarged blind spot and 3 (17%) had restricted visual field. Secondary causes of intracranial hypertension were not identified but the associated conditions were sickle cell disease, Behcet disease, neurofibromatosis type 1, varicella infection, and brucellosis. Seventeen (89%) patients showed good response to treatment with acetazolamide, steroids or both, with resolution of symptoms and signs (p

AB - Idiopathic intracranial hypertension (IIH) is a relatively rare disease in children. It is defined as raised intracranial pressure in the absence of clinical, laboratory or radiological evidence of an intracranial space occupying lesion. We aimed to evaluate the clinical and therapeutic features of IIH in a presenting group of Omani pediatric population. We conducted a retrospective chart review of patients below 18 years of age diagnosed with IIH between 1992 and 2006 according to Dandy's Modified Criteria at Sultan Qaboos University Hospital, Oman. Statistical analyses were conducted using McNemar's test. Nineteen patients were included in the study, 11 (58%) were males and 8 (42%) were females, with a ratio of 1.4:1. The median age at presentation was 8.5 years. The average body mass index of the patients was 18.1 with only 2 (11%) children being obese, both males and pubertal. All the patients except 1 (5%) were symptomatic at presentation. The commonest symptom was headache found in 16 (84%) patients. This was followed by visual symptoms in half of them in the form of diplopia (16%) or transient visual obscuration (37%). All patients had bilateral papilledema, 7 (37%) had visual field defects, 4 (21%) had an enlarged blind spot and 3 (17%) had restricted visual field. Secondary causes of intracranial hypertension were not identified but the associated conditions were sickle cell disease, Behcet disease, neurofibromatosis type 1, varicella infection, and brucellosis. Seventeen (89%) patients showed good response to treatment with acetazolamide, steroids or both, with resolution of symptoms and signs (p

KW - Headache

KW - Idiopathic intracranial hypertension

KW - Papilledema

UR - http://www.scopus.com/inward/record.url?scp=41849147117&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41849147117&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:41849147117

VL - 6

SP - 35

EP - 38

JO - Journal of Pediatric Neuroradiology

JF - Journal of Pediatric Neuroradiology

SN - 1304-2580

IS - 1

ER -