Hypertrophic Obstructive Cardiomyopathy in An Infant with Hemophagocytic Lymphohistiocytosis; Answer to a Riddle

Fatma Rabah; Ismail Beshlawi; Yasser Wali; Abdulhakim Al-Rawas; Khalfan Al Senaidi

doi:10.1097/MPH.0000000000000257

Hypertrophic Obstructive Cardiomyopathy in An Infant with Hemophagocytic Lymphohistiocytosis; Answer to a Riddle

Fatma Rabah, Ismail Beshlawi, Yasser Wali, Abdulhakim Al-Rawas, Khalfan Al Senaidi

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

Familial hemophagocytic lymphohistiocytosis (FHLH) is a hereditary hyperinflammatory condition with T-cell and macrophage activation. Treatment consists of immunosuppressive therapy plus bone marrow transplantation. Cardiac manifestations of FHLH were scarcely mentioned in the literature with conflicting pathophysiological explanations. We report a case of hypertrophic obstructive cardiomyopathy associated with FHLH. Guided by such a case, a clear vision regarding the real cause is thought to be obtained in the cloudy landscape of pathophysiology. ©

Original language	English
Pages (from-to)	459-461
Number of pages	3
Journal	Journal of Pediatric Hematology/Oncology
Volume	37
Issue number	6
DOIs	https://doi.org/10.1097/MPH.0000000000000257
Publication status	Published - Aug 6 2015

Keywords

FHLH
hemophagocytic lymphohistiocytosis
high dose corticosteroid therapy
HOCM
hypertrophic obstructive cardiomyopathy
severe adverse event

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Oncology
Hematology
Medicine(all)

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10.1097/MPH.0000000000000257

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Rabah, F., Beshlawi, I., Wali, Y., Al-Rawas, A., & Al Senaidi, K. (2015). Hypertrophic Obstructive Cardiomyopathy in An Infant with Hemophagocytic Lymphohistiocytosis; Answer to a Riddle. Journal of Pediatric Hematology/Oncology, 37(6), 459-461. https://doi.org/10.1097/MPH.0000000000000257

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