TY - JOUR
T1 - HPLC analysis of furazolidone in goats given the therapeutic dose
AU - Mustafa, A. I.
AU - Ali, B. H.
AU - Satti, A. M.
PY - 1985
Y1 - 1985
N2 - 1. Furazolidone (FZ) was given to Nubian goats at the recommended therapeutic dose of 10 mg/kg body wt, for 5 days. The animals were slaughtered 24 hr after the last dose, and their livers, gluteal muscles, kidneys and hearts analysed for FZ residues by an HPLC method with a detection limit of 0.05μg g-1. 2. The drug was detected in the muscle and liver at concentrations of 0.256 ± 0.009, 0.101 ± 0.016 μg g-1 tissue, respectively. 3. No detectable concentrations of the drug were found in the kidney and heart.
AB - 1. Furazolidone (FZ) was given to Nubian goats at the recommended therapeutic dose of 10 mg/kg body wt, for 5 days. The animals were slaughtered 24 hr after the last dose, and their livers, gluteal muscles, kidneys and hearts analysed for FZ residues by an HPLC method with a detection limit of 0.05μg g-1. 2. The drug was detected in the muscle and liver at concentrations of 0.256 ± 0.009, 0.101 ± 0.016 μg g-1 tissue, respectively. 3. No detectable concentrations of the drug were found in the kidney and heart.
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U2 - 10.1016/0742-8413(85)90109-4
DO - 10.1016/0742-8413(85)90109-4
M3 - Article
C2 - 2861044
AN - SCOPUS:0021834018
SN - 0306-4492
VL - 81
SP - 167
EP - 169
JO - Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
JF - Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
IS - 1
ER -