HLA antigens in Omani psoriasis vulgaris patients

Fatma Al-Mamari*, Ali Al-Shirawi, D. D. Banodkar, Suliman Al-Hashmi, Faiza Al-Yahyaae, Mathew Varghese, J. A. Raeburn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Objectives: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. Methods: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. Results: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. Conclusion: Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6,-Bw57 and-DR7 preponderance in most other ethnic groups.

Original languageEnglish
JournalOman Medical Journal
Volume24
Issue number1
Publication statusPublished - Jan 2009

ASJC Scopus subject areas

  • Medicine(all)

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