HLA antigens in Omani psoriasis vulgaris patients

Fatma Al-Mamari; Ali Al-Shirawi; D. D. Banodkar; Suliman Al-Hashmi; Faiza Al-Yahyaae; Mathew Varghese; J. A. Raeburn

HLA antigens in Omani psoriasis vulgaris patients

Fatma Al-Mamari^*, Ali Al-Shirawi, D. D. Banodkar, Suliman Al-Hashmi, Faiza Al-Yahyaae, Mathew Varghese, J. A. Raeburn

^*Corresponding author for this work

Medicine

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Objectives: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. Methods: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. Results: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. Conclusion: Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6,-Bw57 and-DR7 preponderance in most other ethnic groups.

Original language	English
Journal	Oman Medical Journal
Volume	24
Issue number	1
Publication status	Published - Jan 2009

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "HLA antigens in Omani psoriasis vulgaris patients",

abstract = "Objectives: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. Methods: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. Results: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. Conclusion: Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6,-Bw57 and-DR7 preponderance in most other ethnic groups.",

author = "Fatma Al-Mamari and Ali Al-Shirawi and Banodkar, {D. D.} and Suliman Al-Hashmi and Faiza Al-Yahyaae and Mathew Varghese and Raeburn, {J. A.}",

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journal = "Oman Medical Journal",

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T1 - HLA antigens in Omani psoriasis vulgaris patients

AU - Al-Mamari, Fatma

AU - Al-Shirawi, Ali

AU - Banodkar, D. D.

AU - Al-Hashmi, Suliman

AU - Al-Yahyaae, Faiza

AU - Varghese, Mathew

AU - Raeburn, J. A.

PY - 2009/1

Y1 - 2009/1

N2 - Objectives: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. Methods: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. Results: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. Conclusion: Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6,-Bw57 and-DR7 preponderance in most other ethnic groups.

AB - Objectives: To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population. Methods: Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies. Results: HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86. Conclusion: Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6,-Bw57 and-DR7 preponderance in most other ethnic groups.

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HLA antigens in Omani psoriasis vulgaris patients

Abstract

ASJC Scopus subject areas

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