HLA-A68 and HLA-B15 alleles correlate with poor immune response among AIDS patients on combined antiretroviral therapy

Marah El-Beeli, Samira Hamad Al-Mahrooqi, Randa Mahmoud Youssef, Fahad Zadjali, Abdullah Balkhair, Mohammed Said Al-Balushi, Elias Anthony Said, Sidgi Syed Hasson, Ali Abdullah Al-Jabri*

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Around 15-30% of AIDS patients fail to recover their CD4+ T cell levels following combined antiretroviral therapy despite successful inhibition of HIV-1 replication. The exact reasons for this immune recovery failure are not completely understood. HLA alleles are among the candidate that may explain this failure. A total of 65 adult AIDS patients, with viral load of

Original languageEnglish
JournalHuman Immunology
DOIs
Publication statusAccepted/In press - Feb 5 2014

Keywords

  • AIDS
  • CART
  • HIV
  • HLA
  • Immune response
  • Oman

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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