Highly Sensitive and Selective Voltammetric Sensor Fullerene Modified Glassy Carbon Electrode for Determination of Cefitizoxime in Solubilized System

Rajeev Jain, Jahangir Ahmad Rather, Ashish Dwivedi, Vikas

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The usefulness of fullerene modified glassy carbon electrode in mediating the reduction of cefitizoxime in solubilized system has been demonstrated. Due to the unique structure and extraordinary properties, fullerene shows higher catalytic efficiency towards cefitizoxime reduction. The kinetic parameters, electron transfer coefficient (α) and rate constant (K0) across the modified electrode are 0.37 and 0.1081/s respectively. The proposed square-wave voltammetric method is linear over the concentration range 1.2-10.3 μg/mL. The limit of detection (LOD) is found 0.27 ng/mL. High sensitivity and selectivity together with low detection limit of the electrode response make it suitable for the determination of cefitizoxime.

Original languageEnglish
Pages (from-to)2600-2606
Number of pages7
JournalElectroanalysis
Volume22
Issue number21
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Cefitizoxime (Ceftz.)
  • Cetyltrimethylammonium bromide (CTAB)
  • Fullerene modified glassy carbon electrode (C-GCE)
  • Sensors

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

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