Abstract
A simple, rapid and sensitive chemiluminescent (CL) method for the assay of venlafaxine (VEN) in pharmaceutical formulations and serum samples by a two-chip device is proposed. The method is based on the reaction of this drug with a tris(2,2′-bipyridyl) ruthenium(II)-peroxydisulphate CL system. The optimum chemical conditions for CL emission were investigated. The calibration graph was linear for the concentration range 0.02-8.0 μg/mL. The detection and quantification limits were found to be 0.006 and 0.018 μg/mL, respectively, while the relative standard deviation (RSD) was
Original language | English |
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Pages (from-to) | 44-49 |
Number of pages | 6 |
Journal | Luminescence |
Volume | 28 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 2013 |
Keywords
- chemiluminescence
- microfluidics
- Tris(2,2′-bipyridyl) ruthenium(II)
- two-chip device
- venlafaxine
ASJC Scopus subject areas
- Biophysics
- Chemistry (miscellaneous)
- Medicine(all)