High resolution computed tomography in asthma

Mousa Khadadah, B. Jayakrishnan, Abdulaziz Muquim, Nabil Maradny, Omolara Roberts, Tariq Sinan, Ibrahim Lasheen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objectives: High-resolution computed tomography (HRCT) can detect the structural abnormalities in asthma. This study attempts to correlate these abnormalities with clinical and pulmonary function test (PFT) data. Methods: Consecutive stable asthma patients attending Mubarak Al Kabeer Hospital, Kuwait, were subjected to HRCT during a six month period from July 2004 to December 2004, after initial evaluation and PFT. Results: Of the 28 cases, sixteen (57.1%) had moderate, 6 (21.4%) had mild and 6 (21.4%) had severe persistent asthma. Thirteen (46.4%) patients had asthma for 1 to 5 years and 12 (42.9%) were having asthma for >10 years. Bronchial wall thickening (57.1%), bronchiectasis (28.6%), mucoid impaction (17.9%), mosaic attenuation (10.7%), air trapping (78.6%) and plate like atelectasis (21.4%) were noted. Bronchial wall thickening (p=0.044) and bronchiectasis (p=0.063) were most prevalent in males. Ten (35.7%) patients exhibited mild, 9 (32.1%) had moderate and 3 (10.7%) had severe air trapping. The difference in Hounsfield units between expiratory and inspiratory slices (air trapping) when correlated with percent-predicted FEV1 in right upper (r=0.25; p=0.30), left upper (r=0.20; p=0.41), right mid (r=0.15; p=0.53), left mid (r=-0.04; p=0.60), right lower (r=0.04; p=0.86) and left lower zones (r=-0.13; p=0.58) showed no relation. The same when correlated as above with the percent predicted FEF 25-75 did not show any significant association. The presence of air trapping was compared with sex (p=0.640), nationality (p=1.000), disease duration (p=1.000) and severity of symptoms (p=0.581). Conclusion: Abnormal HRCT findings are common in asthma; however, air trapping when present was not related to the duration or severity of the illness or to the FEV1.

Original languageEnglish
Pages (from-to)145-150
Number of pages6
JournalOman Medical Journal
Volume27
Issue number2
DOIs
Publication statusPublished - 2012

Fingerprint

Asthma
Tomography
Air
Bronchiectasis
Respiratory Function Tests
Maximal Midexpiratory Flow Rate
Kuwait
Pulmonary Atelectasis
Ethnic Groups

Keywords

  • Air trapping
  • Asthma
  • Bronchiectasis
  • Computed tomography
  • HRCT
  • Pulmonary function

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Khadadah, M., Jayakrishnan, B., Muquim, A., Maradny, N., Roberts, O., Sinan, T., & Lasheen, I. (2012). High resolution computed tomography in asthma. Oman Medical Journal, 27(2), 145-150. https://doi.org/10. 5001/omj.2012.30

High resolution computed tomography in asthma. / Khadadah, Mousa; Jayakrishnan, B.; Muquim, Abdulaziz; Maradny, Nabil; Roberts, Omolara; Sinan, Tariq; Lasheen, Ibrahim.

In: Oman Medical Journal, Vol. 27, No. 2, 2012, p. 145-150.

Research output: Contribution to journalArticle

Khadadah, M, Jayakrishnan, B, Muquim, A, Maradny, N, Roberts, O, Sinan, T & Lasheen, I 2012, 'High resolution computed tomography in asthma', Oman Medical Journal, vol. 27, no. 2, pp. 145-150. https://doi.org/10. 5001/omj.2012.30
Khadadah M, Jayakrishnan B, Muquim A, Maradny N, Roberts O, Sinan T et al. High resolution computed tomography in asthma. Oman Medical Journal. 2012;27(2):145-150. https://doi.org/10. 5001/omj.2012.30
Khadadah, Mousa ; Jayakrishnan, B. ; Muquim, Abdulaziz ; Maradny, Nabil ; Roberts, Omolara ; Sinan, Tariq ; Lasheen, Ibrahim. / High resolution computed tomography in asthma. In: Oman Medical Journal. 2012 ; Vol. 27, No. 2. pp. 145-150.
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