Helicobacter pylori. Basics and clinical overview

Mohammed S. Al-Marhoon, Roger W. Soames

Research output: Contribution to journalReview article


The discovery of Helicobacter pylori (H. pylori) has greatly changed the approach to the management of peptic ulcer disease and gastric cancer. A sound knowledge of the basics of H. pylori is an important aid in the diagnosis and treatment of clinical conditions associated with this infection. Gastric carcinoma is estimated to be the world's second most common cancer as a cause of death. It is hoped that gastric cancer can be prevented by H. pylori eradication; however, this issue is still under investigation. Active research is ongoing to highlight the mechanisms by which H. pylori leads to severe gastric diseases as well as finding associations with extra-gastric diseases.

Original languageEnglish
Pages (from-to)524-530
Number of pages7
JournalSaudi Medical Journal
Issue number4
Publication statusPublished - Apr 2005

ASJC Scopus subject areas

  • Medicine(all)

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