Gut microbial communities modulating brain development and function

Maha Al-Asmakh; Farhana Anuar; Fahad Zadjali; Joseph Rafter; Sven Pettersson

doi:10.4161/gmic.21287

Gut microbial communities modulating brain development and function

Maha Al-Asmakh, Farhana Anuar, Fahad Zadjali, Joseph Rafter, Sven Pettersson^*

^*Corresponding author for this work

Biochemistry

Research output: Contribution to journal › Review article › peer-review

87 Citations (Scopus)

Abstract

Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective.

Original language	English
Journal	Gut Microbes
Volume	3
Issue number	4
DOIs	https://doi.org/10.4161/gmic.21287
Publication status	Published - 2012

ASJC Scopus subject areas

Microbiology
Gastroenterology
Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4161/gmic.21287

Cite this

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abstract = "Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective.",

author = "Maha Al-Asmakh and Farhana Anuar and Fahad Zadjali and Joseph Rafter and Sven Pettersson",

note = "Funding Information: We would like to thank Qatar University for the PhD funding of M.A. The authors and their works are supported by grants from VR, Cancerfonden, EU-project TORNADO and Singapore Millenium Foundation. We are also grateful for valuable comments from Velmurugesan Arulampalam.",

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AU - Al-Asmakh, Maha

AU - Anuar, Farhana

AU - Zadjali, Fahad

AU - Rafter, Joseph

AU - Pettersson, Sven

N1 - Funding Information: We would like to thank Qatar University for the PhD funding of M.A. The authors and their works are supported by grants from VR, Cancerfonden, EU-project TORNADO and Singapore Millenium Foundation. We are also grateful for valuable comments from Velmurugesan Arulampalam.

PY - 2012

Y1 - 2012

N2 - Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective.

AB - Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective.

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JF - Gut Microbes

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Gut microbial communities modulating brain development and function

Abstract

ASJC Scopus subject areas

UN SDGs

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