Geographical clustering of juvenile onset systemic lupus erythematosus within the Sultanate of Oman

Reem Abdwani, Safiya Al-Abrawi, Sharef Waadallah Sharef, Ibrahim Al-Zakwani

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify geographical clustering and to compare the demographic, clinical, and immunological characteristics of this cluster against the rest of Oman. Methods: We retrospectively reviewed the hospital charts of 104 consecutive children with childhood onset SLE who were seen in pediatric rheumatology centers in the Sultanate of Oman over a 15- year period between 1995 and 2010. Results: Geographical clustering of childhood onset SLE was identified in Sharqiya region, which constituted 41% (n=43) of all cases in Oman. This cohort of patients had characteristic disease features which consisted of significantly more boys affected with SLE compared to the rest of the country (42% versus 15%; p=0.002). These children also tended to be younger (10.3 versus 16.5 years; p=0.001), diagnosed at an earlier age (6.4 versus 9.4 years; p

Original languageEnglish
Pages (from-to)199-203
Number of pages5
JournalOman Medical Journal
Volume28
Issue number3
DOIs
Publication statusPublished - 2013

Fingerprint

Oman
Systemic Lupus Erythematosus
Cluster Analysis
Rheumatology
Demography
Pediatrics

Keywords

  • Demography
  • Lupus
  • Oman
  • SLE

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Geographical clustering of juvenile onset systemic lupus erythematosus within the Sultanate of Oman. / Abdwani, Reem; Al-Abrawi, Safiya; Sharef, Sharef Waadallah; Al-Zakwani, Ibrahim.

In: Oman Medical Journal, Vol. 28, No. 3, 2013, p. 199-203.

Research output: Contribution to journalArticle

@article{11541e52e74848c1956895fcd32c88b8,
title = "Geographical clustering of juvenile onset systemic lupus erythematosus within the Sultanate of Oman",
abstract = "Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify geographical clustering and to compare the demographic, clinical, and immunological characteristics of this cluster against the rest of Oman. Methods: We retrospectively reviewed the hospital charts of 104 consecutive children with childhood onset SLE who were seen in pediatric rheumatology centers in the Sultanate of Oman over a 15- year period between 1995 and 2010. Results: Geographical clustering of childhood onset SLE was identified in Sharqiya region, which constituted 41{\%} (n=43) of all cases in Oman. This cohort of patients had characteristic disease features which consisted of significantly more boys affected with SLE compared to the rest of the country (42{\%} versus 15{\%}; p=0.002). These children also tended to be younger (10.3 versus 16.5 years; p=0.001), diagnosed at an earlier age (6.4 versus 9.4 years; p",
keywords = "Demography, Lupus, Oman, SLE",
author = "Reem Abdwani and Safiya Al-Abrawi and Sharef, {Sharef Waadallah} and Ibrahim Al-Zakwani",
year = "2013",
doi = "10.5001/omj.2013.54",
language = "English",
volume = "28",
pages = "199--203",
journal = "Oman Medical Journal",
issn = "1999-768X",
publisher = "Oman Medical Specialty Board",
number = "3",

}

TY - JOUR

T1 - Geographical clustering of juvenile onset systemic lupus erythematosus within the Sultanate of Oman

AU - Abdwani, Reem

AU - Al-Abrawi, Safiya

AU - Sharef, Sharef Waadallah

AU - Al-Zakwani, Ibrahim

PY - 2013

Y1 - 2013

N2 - Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify geographical clustering and to compare the demographic, clinical, and immunological characteristics of this cluster against the rest of Oman. Methods: We retrospectively reviewed the hospital charts of 104 consecutive children with childhood onset SLE who were seen in pediatric rheumatology centers in the Sultanate of Oman over a 15- year period between 1995 and 2010. Results: Geographical clustering of childhood onset SLE was identified in Sharqiya region, which constituted 41% (n=43) of all cases in Oman. This cohort of patients had characteristic disease features which consisted of significantly more boys affected with SLE compared to the rest of the country (42% versus 15%; p=0.002). These children also tended to be younger (10.3 versus 16.5 years; p=0.001), diagnosed at an earlier age (6.4 versus 9.4 years; p

AB - Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify geographical clustering and to compare the demographic, clinical, and immunological characteristics of this cluster against the rest of Oman. Methods: We retrospectively reviewed the hospital charts of 104 consecutive children with childhood onset SLE who were seen in pediatric rheumatology centers in the Sultanate of Oman over a 15- year period between 1995 and 2010. Results: Geographical clustering of childhood onset SLE was identified in Sharqiya region, which constituted 41% (n=43) of all cases in Oman. This cohort of patients had characteristic disease features which consisted of significantly more boys affected with SLE compared to the rest of the country (42% versus 15%; p=0.002). These children also tended to be younger (10.3 versus 16.5 years; p=0.001), diagnosed at an earlier age (6.4 versus 9.4 years; p

KW - Demography

KW - Lupus

KW - Oman

KW - SLE

UR - http://www.scopus.com/inward/record.url?scp=84878930233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878930233&partnerID=8YFLogxK

U2 - 10.5001/omj.2013.54

DO - 10.5001/omj.2013.54

M3 - Article

C2 - 23772287

AN - SCOPUS:84878930233

VL - 28

SP - 199

EP - 203

JO - Oman Medical Journal

JF - Oman Medical Journal

SN - 1999-768X

IS - 3

ER -