Geographical clustering of juvenile onset systemic lupus erythematosus within the Sultanate of Oman

Reem Abdwani, Safiya Al-Abrawi, Sharef Waadallah Sharef, Ibrahim Al-Zakwani

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify geographical clustering and to compare the demographic, clinical, and immunological characteristics of this cluster against the rest of Oman. Methods: We retrospectively reviewed the hospital charts of 104 consecutive children with childhood onset SLE who were seen in pediatric rheumatology centers in the Sultanate of Oman over a 15- year period between 1995 and 2010. Results: Geographical clustering of childhood onset SLE was identified in Sharqiya region, which constituted 41% (n=43) of all cases in Oman. This cohort of patients had characteristic disease features which consisted of significantly more boys affected with SLE compared to the rest of the country (42% versus 15%; p=0.002). These children also tended to be younger (10.3 versus 16.5 years; p=0.001), diagnosed at an earlier age (6.4 versus 9.4 years; p

Original languageEnglish
Pages (from-to)199-203
Number of pages5
JournalOman Medical Journal
Volume28
Issue number3
DOIs
Publication statusPublished - 2013

Keywords

  • Demography
  • Lupus
  • Oman
  • SLE

ASJC Scopus subject areas

  • Medicine(all)

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