Genomic 3′ terminal sequence comparison of three isolates of rabbit haemorrhagic disease virus

I. D. Milton, R. Vlasak, N. Nowotny, L. Rodak, M. J. Carter

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Comparison of sequence data is necessary in older to investigate virus origins, identify features common to virulent strains, and characterize genomic organization within virus families. A virulent caliciviral disease of rabbits recently emerged in China. We have sequenced 1100 bases from the 3′ ends of two independent European isolates of this virus, and compared these with previously determined calicivirus sequences. Rabbit caliciviruses were closely related, despite the different countries in which isolation was made. This supports the rapid spread of a new virus across Europe. The capsid protein sequences of these rabbit viruses differ markedly from those determined for feline calicivirus, but a hypothetical 3′ open reading frame is relatively well conserved between the caliciviruses of these two different hosts and argues for a functional role.

Original languageEnglish
Pages (from-to)37-42
Number of pages6
JournalFEMS Microbiology Letters
Volume93
Issue number1
DOIs
Publication statusPublished - May 15 1992

Fingerprint

Rabbit Haemorrhagic Disease Virus
Viruses
Rabbits
Feline Calicivirus
Capsid Proteins
Open Reading Frames
China

Keywords

  • Nucleotide sequence comparison
  • Rabbit calicivirus

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Microbiology

Cite this

Genomic 3′ terminal sequence comparison of three isolates of rabbit haemorrhagic disease virus. / Milton, I. D.; Vlasak, R.; Nowotny, N.; Rodak, L.; Carter, M. J.

In: FEMS Microbiology Letters, Vol. 93, No. 1, 15.05.1992, p. 37-42.

Research output: Contribution to journalArticle

Milton, I. D. ; Vlasak, R. ; Nowotny, N. ; Rodak, L. ; Carter, M. J. / Genomic 3′ terminal sequence comparison of three isolates of rabbit haemorrhagic disease virus. In: FEMS Microbiology Letters. 1992 ; Vol. 93, No. 1. pp. 37-42.
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