Twenty-nine Plasmodium falciparum isolates from patients in Asar village, eastern Sudan, were characterized for variation in 18 different genetically controlled characters, including iso-enzymes, proteins detected by two-dimensional polyacrylamide gel electrophoresis and blood-stage antigens. Considerable allelic diversity in the genes determining these characters was detected. Each isolate contained genetically distinct parasites. Fifteen individuals were infected with more than one parasite genotype. The diversity of parasite types is most probably generated by recombination during mosquito transmission of mixed parasite clones.
|Number of pages||6|
|Journal||Transactions of the Royal Society of Tropical Medicine and Hygiene|
|Publication status||Published - 1991|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Infectious Diseases