Abstract
Twenty-nine Plasmodium falciparum isolates from patients in Asar village, eastern Sudan, were characterized for variation in 18 different genetically controlled characters, including iso-enzymes, proteins detected by two-dimensional polyacrylamide gel electrophoresis and blood-stage antigens. Considerable allelic diversity in the genes determining these characters was detected. Each isolate contained genetically distinct parasites. Fifteen individuals were infected with more than one parasite genotype. The diversity of parasite types is most probably generated by recombination during mosquito transmission of mixed parasite clones.
| Original language | English |
|---|---|
| Pages (from-to) | 572-577 |
| Number of pages | 6 |
| Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| Volume | 85 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1991 |
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ASJC Scopus subject areas
- Parasitology
- Medicine(all)
Cite this
Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens. / Babiker, Hamza Ali; Creasey, Alison M.; Fenton, Brian; Bayoumi, Riad A L; Arnot, David E.; Walliker, David.
In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 85, No. 5, 1991, p. 572-577.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens
AU - Babiker, Hamza Ali
AU - Creasey, Alison M.
AU - Fenton, Brian
AU - Bayoumi, Riad A L
AU - Arnot, David E.
AU - Walliker, David
PY - 1991
Y1 - 1991
N2 - Twenty-nine Plasmodium falciparum isolates from patients in Asar village, eastern Sudan, were characterized for variation in 18 different genetically controlled characters, including iso-enzymes, proteins detected by two-dimensional polyacrylamide gel electrophoresis and blood-stage antigens. Considerable allelic diversity in the genes determining these characters was detected. Each isolate contained genetically distinct parasites. Fifteen individuals were infected with more than one parasite genotype. The diversity of parasite types is most probably generated by recombination during mosquito transmission of mixed parasite clones.
AB - Twenty-nine Plasmodium falciparum isolates from patients in Asar village, eastern Sudan, were characterized for variation in 18 different genetically controlled characters, including iso-enzymes, proteins detected by two-dimensional polyacrylamide gel electrophoresis and blood-stage antigens. Considerable allelic diversity in the genes determining these characters was detected. Each isolate contained genetically distinct parasites. Fifteen individuals were infected with more than one parasite genotype. The diversity of parasite types is most probably generated by recombination during mosquito transmission of mixed parasite clones.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026001603&partnerID=8YFLogxK
U2 - 10.1016/0035-9203(91)90347-2
DO - 10.1016/0035-9203(91)90347-2
M3 - Article
VL - 85
SP - 572
EP - 577
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
SN - 0035-9203
IS - 5
ER -