Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens

Hamza Ali Babiker; Alison M. Creasey; Brian Fenton; Riad A L Bayoumi; David E. Arnot; David Walliker

doi:10.1016/0035-9203(91)90347-2

Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens

Hamza Ali Babiker^*, Alison M. Creasey, Brian Fenton, Riad A L Bayoumi, David E. Arnot, David Walliker

^*Corresponding author for this work

Biochemistry

Research output: Contribution to journal › Article › peer-review

74 Citations (Scopus)

Abstract

Twenty-nine Plasmodium falciparum isolates from patients in Asar village, eastern Sudan, were characterized for variation in 18 different genetically controlled characters, including iso-enzymes, proteins detected by two-dimensional polyacrylamide gel electrophoresis and blood-stage antigens. Considerable allelic diversity in the genes determining these characters was detected. Each isolate contained genetically distinct parasites. Fifteen individuals were infected with more than one parasite genotype. The diversity of parasite types is most probably generated by recombination during mosquito transmission of mixed parasite clones.

Original language	English
Pages (from-to)	572-577
Number of pages	6
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	85
Issue number	5
DOIs	https://doi.org/10.1016/0035-9203(91)90347-2
Publication status	Published - 1991

ASJC Scopus subject areas

Parasitology
Medicine(all)

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Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens. / Babiker, Hamza Ali; Creasey, Alison M.; Fenton, Brian; Bayoumi, Riad A L; Arnot, David E.; Walliker, David.

In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 85, No. 5, 1991, p. 572-577.

Research output: Contribution to journal › Article › peer-review

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