TY - JOUR
T1 - Foot care education and platelet derived growth factor on wound healing in foot ulcers among adults
AU - D'Souza, Melba Sheila
AU - D'Souza, Jennifer
AU - Karkada, Subrahmanya Nairy
N1 - Publisher Copyright:
© 2016 International Journal of Nutrition, Pharmacology, Neurological Diseases | Published by Wolters Kluwer - Medknow.
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Aim: The aim of the study was to evaluate the combined efficacy of foot care education and recombinant human platelet-derived growth factor (rhPDGF) on the wound healing in foot ulcers among adults with type 2 diabetes (T2D). Subjects and Methods: A randomized control trial and a factorial design were used in this study in a 500-bedded private teaching hospital with four major surgical units in 2013. A sample size of 50 adults with T2D was selected in each of the three groups; the combined intervention (foot education and rhPDGF), the medication intervention (rhPDGF), and the control group (CG) (Betadine gel). A standard clinical practice guideline was adopted for the three groups at baseline, 15 th day, and 30 th day. A modified Bates-Jensen wound assessment tool was used to assess the wound healing. Results: Combined efficacy of foot care education and rhPDGF resulted in complete closure of wound with a mean time of 15.91 days compared to the medication intervention (rhPDGF) and the CG in foot ulcers. There was better wound healing characteristics among adults with T2D exposed to the foot care education and rhPDGF compared to the use of rhPDGF and Betadine. Conclusion: Combined efficacy of foot care education with PDGF improved the total wound healing and ensured better wound characteristics in lower extremity foot ulcers among adults with T2D.
AB - Aim: The aim of the study was to evaluate the combined efficacy of foot care education and recombinant human platelet-derived growth factor (rhPDGF) on the wound healing in foot ulcers among adults with type 2 diabetes (T2D). Subjects and Methods: A randomized control trial and a factorial design were used in this study in a 500-bedded private teaching hospital with four major surgical units in 2013. A sample size of 50 adults with T2D was selected in each of the three groups; the combined intervention (foot education and rhPDGF), the medication intervention (rhPDGF), and the control group (CG) (Betadine gel). A standard clinical practice guideline was adopted for the three groups at baseline, 15 th day, and 30 th day. A modified Bates-Jensen wound assessment tool was used to assess the wound healing. Results: Combined efficacy of foot care education and rhPDGF resulted in complete closure of wound with a mean time of 15.91 days compared to the medication intervention (rhPDGF) and the CG in foot ulcers. There was better wound healing characteristics among adults with T2D exposed to the foot care education and rhPDGF compared to the use of rhPDGF and Betadine. Conclusion: Combined efficacy of foot care education with PDGF improved the total wound healing and ensured better wound characteristics in lower extremity foot ulcers among adults with T2D.
KW - Betadine
KW - Diabetes
KW - Foot care clinical practice guidelines
KW - Foot care education
KW - Foot ulcer
KW - Platelet derived growth factor
KW - Wound healing
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U2 - 10.4103/2231-0738.184583
DO - 10.4103/2231-0738.184583
M3 - Article
AN - SCOPUS:84977603218
SN - 2231-0738
VL - 6
SP - 111
EP - 118
JO - International Journal of Nutrition, Pharmacology, Neurological Diseases
JF - International Journal of Nutrition, Pharmacology, Neurological Diseases
IS - 3
ER -
