Foot care education and platelet derived growth factor on wound healing in foot ulcers among adults

Melba Sheila D'Souza, Jennifer D'Souza, Subrahmanya Nairy Karkada

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Aim: The aim of the study was to evaluate the combined efficacy of foot care education and recombinant human platelet-derived growth factor (rhPDGF) on the wound healing in foot ulcers among adults with type 2 diabetes (T2D). Subjects and Methods: A randomized control trial and a factorial design were used in this study in a 500-bedded private teaching hospital with four major surgical units in 2013. A sample size of 50 adults with T2D was selected in each of the three groups; the combined intervention (foot education and rhPDGF), the medication intervention (rhPDGF), and the control group (CG) (Betadine gel). A standard clinical practice guideline was adopted for the three groups at baseline, 15 th day, and 30 th day. A modified Bates-Jensen wound assessment tool was used to assess the wound healing. Results: Combined efficacy of foot care education and rhPDGF resulted in complete closure of wound with a mean time of 15.91 days compared to the medication intervention (rhPDGF) and the CG in foot ulcers. There was better wound healing characteristics among adults with T2D exposed to the foot care education and rhPDGF compared to the use of rhPDGF and Betadine. Conclusion: Combined efficacy of foot care education with PDGF improved the total wound healing and ensured better wound characteristics in lower extremity foot ulcers among adults with T2D.

Original languageEnglish
Pages (from-to)111-118
Number of pages8
JournalInternational Journal of Nutrition, Pharmacology, Neurological Diseases
Volume6
Issue number3
DOIs
Publication statusPublished - Jul 1 2016

Fingerprint

Foot Ulcer
Platelet-Derived Growth Factor
Wound Healing
Foot
Education
Type 2 Diabetes Mellitus
Povidone-Iodine
Wounds and Injuries
Control Groups
Private Hospitals
Practice Guidelines
Teaching Hospitals
Sample Size
Lower Extremity
Gels

Keywords

  • Betadine
  • Diabetes
  • Foot care clinical practice guidelines
  • Foot care education
  • Foot ulcer
  • Platelet derived growth factor
  • Wound healing

ASJC Scopus subject areas

  • Clinical Neurology
  • Pharmacology (medical)
  • Nutrition and Dietetics

Cite this

Foot care education and platelet derived growth factor on wound healing in foot ulcers among adults. / D'Souza, Melba Sheila; D'Souza, Jennifer; Karkada, Subrahmanya Nairy.

In: International Journal of Nutrition, Pharmacology, Neurological Diseases, Vol. 6, No. 3, 01.07.2016, p. 111-118.

Research output: Contribution to journalArticle

D'Souza, Melba Sheila ; D'Souza, Jennifer ; Karkada, Subrahmanya Nairy. / Foot care education and platelet derived growth factor on wound healing in foot ulcers among adults. In: International Journal of Nutrition, Pharmacology, Neurological Diseases. 2016 ; Vol. 6, No. 3. pp. 111-118.
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