Follicular dendritic cell sarcoma: Cytogenetics and pathological findings

Achandira M. Udayakumar, Maiya Al-Bahri, Ikram A. Burney, Ibrahim Al-Haddabi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious presentation further complicated by the difficult diagnostic and therapeutic assessment. It has a low to intermediate risk of recurrence and metastasis. Unlike other soft tissue sarcomas or histiocytic and dendritic cell neoplasms, cytogenetic studies are very limited in FDCS cases. Although no specific chromosomal marker has yet been established, complex aberrations and different ploidy types have been documented. We report the case of a 39-yearold woman with FDCS who presented to the Sultan Qaboos University Hospital in Muscat, Oman, in February 2013. Ultrastructural, immunophenotypical and histological findings are reported. In addition, karyotypic findings showed deletions of the chromosomes 1p, 3q, 6q, 7q, 8q and 11q. To the best of the authors’ knowledge, these have not been reported previously in this tumour.

Original languageEnglish
Pages (from-to)e411-e414
JournalSultan Qaboos University Medical Journal
Volume15
Issue number3
DOIs
Publication statusPublished - 2015

Fingerprint

Follicular Dendritic Cell Sarcoma
Cytogenetics
Oman
Neoplasms
Ploidies
Sarcoma
Dendritic Cells
Neoplasm Metastasis
Recurrence
Therapeutics

Keywords

  • Case report
  • Chromosomal aberrations
  • Cytogenetics
  • Fine needle aspiration
  • Follicular dendritic cell sarcoma
  • Karyotyping
  • Oman

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Follicular dendritic cell sarcoma : Cytogenetics and pathological findings. / Udayakumar, Achandira M.; Al-Bahri, Maiya; Burney, Ikram A.; Al-Haddabi, Ibrahim.

In: Sultan Qaboos University Medical Journal, Vol. 15, No. 3, 2015, p. e411-e414.

Research output: Contribution to journalArticle

@article{7b341fdaed0945b5897b668b2d76aaee,
title = "Follicular dendritic cell sarcoma: Cytogenetics and pathological findings",
abstract = "Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious presentation further complicated by the difficult diagnostic and therapeutic assessment. It has a low to intermediate risk of recurrence and metastasis. Unlike other soft tissue sarcomas or histiocytic and dendritic cell neoplasms, cytogenetic studies are very limited in FDCS cases. Although no specific chromosomal marker has yet been established, complex aberrations and different ploidy types have been documented. We report the case of a 39-yearold woman with FDCS who presented to the Sultan Qaboos University Hospital in Muscat, Oman, in February 2013. Ultrastructural, immunophenotypical and histological findings are reported. In addition, karyotypic findings showed deletions of the chromosomes 1p, 3q, 6q, 7q, 8q and 11q. To the best of the authors’ knowledge, these have not been reported previously in this tumour.",
keywords = "Case report, Chromosomal aberrations, Cytogenetics, Fine needle aspiration, Follicular dendritic cell sarcoma, Karyotyping, Oman",
author = "Udayakumar, {Achandira M.} and Maiya Al-Bahri and Burney, {Ikram A.} and Ibrahim Al-Haddabi",
year = "2015",
doi = "10.18295/squmj.2015.15.03.017",
language = "English",
volume = "15",
pages = "e411--e414",
journal = "Sultan Qaboos University Medical Journal",
issn = "2075-051X",
publisher = "Sultan Qaboos University",
number = "3",

}

TY - JOUR

T1 - Follicular dendritic cell sarcoma

T2 - Cytogenetics and pathological findings

AU - Udayakumar, Achandira M.

AU - Al-Bahri, Maiya

AU - Burney, Ikram A.

AU - Al-Haddabi, Ibrahim

PY - 2015

Y1 - 2015

N2 - Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious presentation further complicated by the difficult diagnostic and therapeutic assessment. It has a low to intermediate risk of recurrence and metastasis. Unlike other soft tissue sarcomas or histiocytic and dendritic cell neoplasms, cytogenetic studies are very limited in FDCS cases. Although no specific chromosomal marker has yet been established, complex aberrations and different ploidy types have been documented. We report the case of a 39-yearold woman with FDCS who presented to the Sultan Qaboos University Hospital in Muscat, Oman, in February 2013. Ultrastructural, immunophenotypical and histological findings are reported. In addition, karyotypic findings showed deletions of the chromosomes 1p, 3q, 6q, 7q, 8q and 11q. To the best of the authors’ knowledge, these have not been reported previously in this tumour.

AB - Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious presentation further complicated by the difficult diagnostic and therapeutic assessment. It has a low to intermediate risk of recurrence and metastasis. Unlike other soft tissue sarcomas or histiocytic and dendritic cell neoplasms, cytogenetic studies are very limited in FDCS cases. Although no specific chromosomal marker has yet been established, complex aberrations and different ploidy types have been documented. We report the case of a 39-yearold woman with FDCS who presented to the Sultan Qaboos University Hospital in Muscat, Oman, in February 2013. Ultrastructural, immunophenotypical and histological findings are reported. In addition, karyotypic findings showed deletions of the chromosomes 1p, 3q, 6q, 7q, 8q and 11q. To the best of the authors’ knowledge, these have not been reported previously in this tumour.

KW - Case report

KW - Chromosomal aberrations

KW - Cytogenetics

KW - Fine needle aspiration

KW - Follicular dendritic cell sarcoma

KW - Karyotyping

KW - Oman

UR - http://www.scopus.com/inward/record.url?scp=84940021398&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940021398&partnerID=8YFLogxK

U2 - 10.18295/squmj.2015.15.03.017

DO - 10.18295/squmj.2015.15.03.017

M3 - Article

AN - SCOPUS:84940021398

VL - 15

SP - e411-e414

JO - Sultan Qaboos University Medical Journal

JF - Sultan Qaboos University Medical Journal

SN - 2075-051X

IS - 3

ER -