Follicular dendritic cell sarcoma: Cytogenetics and pathological findings

Achandira M. Udayakumar*, Maiya Al-Bahri, Ikram A. Burney, Ibrahim Al-Haddabi

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious presentation further complicated by the difficult diagnostic and therapeutic assessment. It has a low to intermediate risk of recurrence and metastasis. Unlike other soft tissue sarcomas or histiocytic and dendritic cell neoplasms, cytogenetic studies are very limited in FDCS cases. Although no specific chromosomal marker has yet been established, complex aberrations and different ploidy types have been documented. We report the case of a 39-yearold woman with FDCS who presented to the Sultan Qaboos University Hospital in Muscat, Oman, in February 2013. Ultrastructural, immunophenotypical and histological findings are reported. In addition, karyotypic findings showed deletions of the chromosomes 1p, 3q, 6q, 7q, 8q and 11q. To the best of the authors’ knowledge, these have not been reported previously in this tumour.

Original languageEnglish
Pages (from-to)e411-e414
JournalSultan Qaboos University Medical Journal
Volume15
Issue number3
DOIs
Publication statusPublished - 2015

Keywords

  • Case report
  • Chromosomal aberrations
  • Cytogenetics
  • Fine needle aspiration
  • Follicular dendritic cell sarcoma
  • Karyotyping
  • Oman

ASJC Scopus subject areas

  • Medicine(all)

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