Abstract
Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.
| Original language | English |
|---|---|
| Pages (from-to) | 539-543 |
| Number of pages | 5 |
| Journal | Analytical Sciences |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2001 |
ASJC Scopus subject areas
- Analytical Chemistry
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Cite this
Al-Kindy, S. M. Z., Suliman, F. E. O., & Al-Hamadi, A. A. (2001). Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media. Analytical Sciences, 17(4), 539-543. https://doi.org/10.2116/analsci.17.539