Abstract
Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.
| Original language | English |
|---|---|
| Pages (from-to) | 539-543 |
| Number of pages | 5 |
| Journal | Analytical Sciences |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2001 |
Fingerprint
ASJC Scopus subject areas
- Analytical Chemistry
Cite this
Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media. / Al-Kindy, S. M Z; Suliman, F. E O; Al-Hamadi, A. A.
In: Analytical Sciences, Vol. 17, No. 4, 2001, p. 539-543.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media
AU - Al-Kindy, S. M Z
AU - Suliman, F. E O
AU - Al-Hamadi, A. A.
PY - 2001
Y1 - 2001
N2 - Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.
AB - Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.
UR - http://www.scopus.com/inward/record.url?scp=0035022959&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035022959&partnerID=8YFLogxK
U2 - 10.2116/analsci.17.539
DO - 10.2116/analsci.17.539
M3 - Article
C2 - 11990574
AN - SCOPUS:0035022959
VL - 17
SP - 539
EP - 543
JO - Analytical Sciences
JF - Analytical Sciences
SN - 0910-6340
IS - 4
ER -