Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media

S. M Z Al-Kindy; F. E O Suliman; A. A. Al-Hamadi

doi:10.2116/analsci.17.539

Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media

S. M Z Al-Kindy^*, F. E O Suliman, A. A. Al-Hamadi

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 10⁵ mol^-2 l² was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.

Original language	English
Pages (from-to)	539-543
Number of pages	5
Journal	Analytical Sciences
Volume	17
Issue number	4
DOIs	https://doi.org/10.2116/analsci.17.539
Publication status	Published - 2001

ASJC Scopus subject areas

Analytical Chemistry

Access to Document

10.2116/analsci.17.539

Fingerprint Dive into the research topics of 'Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media'. Together they form a unique fingerprint.

Cite this

@article{279822664050429c9b8bd11be21529e6,

title = "Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media",

abstract = "Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.",

author = "Al-Kindy, {S. M Z} and Suliman, {F. E O} and Al-Hamadi, {A. A.}",

year = "2001",

doi = "10.2116/analsci.17.539",

language = "English",

volume = "17",

pages = "539--543",

journal = "Analytical Sciences",

issn = "0910-6340",

publisher = "Japan Society for Analytical Chemistry",

number = "4",

}

TY - JOUR

T1 - Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media

AU - Al-Kindy, S. M Z

AU - Suliman, F. E O

AU - Al-Hamadi, A. A.

PY - 2001

Y1 - 2001

N2 - Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.

AB - Coumarin-6-sulfonyl (6-CS) amino acid derivatives form inclusion complexes with α- and β-cyclodextrins (CD) in aqueous solution. The stoichiometry of the inclusion complex and the equilibrium constant were investigated. Using a fluorescence technique and alanine-β-CD as a model, a 1:2 guest-host complex was established, and K = 4.7 × 105 mol-2 l2 was obtained. Fluorescence enhancement was observed for all derivatives studied, with glycine exhibiting a greater enhancement, and tyrosine showing the least. The stability of the inclusion complex was found to depend on the respective sizes of the guest-host complex and their interaction.

UR - http://www.scopus.com/inward/record.url?scp=0035022959&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035022959&partnerID=8YFLogxK

U2 - 10.2116/analsci.17.539

DO - 10.2116/analsci.17.539

M3 - Article

C2 - 11990574

AN - SCOPUS:0035022959

VL - 17

SP - 539

EP - 543

JO - Analytical Sciences

JF - Analytical Sciences

SN - 0910-6340

IS - 4

ER -

Fluorescence enhancement of coumarin-6-sulfonyl chloride amino acid derivatives in cyclodextrin media

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this