TY - JOUR
T1 - Favourable outcomes of non-O1, non-O139 Vibrio cholerae bacteraemia in vulnerable populations: a case series
T2 - a case series
AU - Al-Farsi, Fatma
AU - Al-Siyabi, Turkiya
AU - Al-Adawi, Badriya
AU - Al-Tai, Amal
N1 - Publisher Copyright:
© 2022 The Author(s)
PY - 2022/6
Y1 - 2022/6
N2 - Background: Non-O1, non-O139 Vibrio cholerae (NOVC) bacteraemia is an uncommon infection and could be associated with life-threatening conditions in susceptible hosts. Definitive management guidelines are lacking. Aim: To describe the clinical spectrum, treatment practices and outcome of NOVC bacteraemia. Methods: Eight patients with NOVC bacteraemia admitted to two large tertiary care hospitals in Oman were identified over a 10-year period (2010–2020). Data were extracted retrospectively from the hospital patient data management. Results: Six (75.0%) patients were male, and the median age of patients was 67.5 years. The majority of cases (87.5%) were not associated with travel and no clear sources were identified. All patients had predisposing factors including diabetes mellitus, chronic liver disease or malignancies. Gastrointestinal symptoms were the predominant manifestations in 75.0% of cases, but diarrhoea was only reported in one patient. Conclusions: Early presentation (median interval from symptom onset to presentation 1.5 days), appropriate management and highly susceptible isolates may have contributed to the favourable outcome, as there were no cases of death or severe course of infection. All patients were discharged home after a median of 9 days of hospitalization.
AB - Background: Non-O1, non-O139 Vibrio cholerae (NOVC) bacteraemia is an uncommon infection and could be associated with life-threatening conditions in susceptible hosts. Definitive management guidelines are lacking. Aim: To describe the clinical spectrum, treatment practices and outcome of NOVC bacteraemia. Methods: Eight patients with NOVC bacteraemia admitted to two large tertiary care hospitals in Oman were identified over a 10-year period (2010–2020). Data were extracted retrospectively from the hospital patient data management. Results: Six (75.0%) patients were male, and the median age of patients was 67.5 years. The majority of cases (87.5%) were not associated with travel and no clear sources were identified. All patients had predisposing factors including diabetes mellitus, chronic liver disease or malignancies. Gastrointestinal symptoms were the predominant manifestations in 75.0% of cases, but diarrhoea was only reported in one patient. Conclusions: Early presentation (median interval from symptom onset to presentation 1.5 days), appropriate management and highly susceptible isolates may have contributed to the favourable outcome, as there were no cases of death or severe course of infection. All patients were discharged home after a median of 9 days of hospitalization.
KW - Bacteraemia
KW - Liver cirrhosis
KW - Non-O1
KW - Vibrio cholerae
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U2 - 10.1016/j.ijregi.2022.03.006
DO - 10.1016/j.ijregi.2022.03.006
M3 - Article
C2 - 35755472
AN - SCOPUS:85150878554
VL - 3
SP - 76
EP - 78
JO - International Journal of Infectious Diseases Regions
JF - International Journal of Infectious Diseases Regions
ER -