Factors contributing to the spread of odontogenic infections a prospective pilot study

Abdulaziz A. Bakathir, Khursheed F. Moos, Ashraf F. Ayoub, Jeremy Bagg

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives: Spreading odontogenic infections (SOI) are the commonest type of serious infections encountered in the orofacial region. A prospective multi-centre study was conducted in the West of Scotland to investigate the contributing role of social, systemic and microbial factors in the pathogenesis of SOI. Methods: Twenty-five patients with severe odontogenic infections were recruited over a period of six months. At admission, clinical assessment included temperature rise, haematological and biochemical investigations. Demographic data, social and past medical histories were obtained. Microbiology samples were collected to identify causative microorganisms and the clinical management of each infection was recorded. Results: Most infections were associated with teeth or roots. Eighty percent of the patients were tobacco smokers and 72% came from deprived areas. Five patients were intravenous drug users, four admitted chronic alcohol abuse, six had underlying systemic disorders and two were at high risk of malnutrition. A raised C-reactive protein at admission was a useful indicator of the severity of infection. Inappropriate prior antibiotic treatment in the absence of surgical drainage was common. Microbiology results showed a predominance of strict anaerobes, notably anaerobic streptococci, Prevotella and Fusobacterium species. Conclusion: SOIs remain surprisingly common and our present pilot study showed a particular association with social deprivation and tobacco smoking. Further elucidation of the role of malnutrition in SOI would be of interest. Molecular characterisation of the microflora associated with SOI may help to highlight whether bacterial factors play a role in converting a localised dentoalveolar abscess into a serious, spreading odontogenic infection.

Original languageEnglish
Pages (from-to)296-304
Number of pages9
JournalSultan Qaboos University Medical Journal
Volume9
Issue number3
Publication statusPublished - Dec 1 2009

Fingerprint

Prospective Studies
Infection
Microbiology
Malnutrition
Fusobacterium
Prevotella
Tooth Root
Scotland
Drug Users
Streptococcus
C-Reactive Protein
Abscess
Alcoholism
Tobacco
Drainage
Smoking
Demography
Anti-Bacterial Agents
Temperature

Keywords

  • Anaerobic bacteria
  • Complications
  • Dental focal infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Factors contributing to the spread of odontogenic infections a prospective pilot study. / Bakathir, Abdulaziz A.; Moos, Khursheed F.; Ayoub, Ashraf F.; Bagg, Jeremy.

In: Sultan Qaboos University Medical Journal, Vol. 9, No. 3, 01.12.2009, p. 296-304.

Research output: Contribution to journalArticle

Bakathir, Abdulaziz A. ; Moos, Khursheed F. ; Ayoub, Ashraf F. ; Bagg, Jeremy. / Factors contributing to the spread of odontogenic infections a prospective pilot study. In: Sultan Qaboos University Medical Journal. 2009 ; Vol. 9, No. 3. pp. 296-304.
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