Expression of the oxytocin gene, but not the vasopressin gene, in the rat uterus during pregnancy

Influence of oestradiol and progesterone

Thomas Bossmar, N. Osman, E. Zilahi, M. A. El Haj, N. Nowotny, J. M. Conlon

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Oxytocin (OT) and vasopressin (VP) are neurohypophyseal hormones with potent stimulatory actions on the uterus. In order to determine whether these hormones may have a paracrine action on the uterus, OT and VP gene expression was studied in myometrium from pregnant rats at gestational ages of 14 and 20 days, and from ovariectomized animals treated with oestradiol and progesterone. OT and VP mRNA concentrations were measured using real-time quantitative reverse transcription-PCR, and OT- and VP-like immunoreactivities were determined using RIA. OT mRNA was detected in the uterus from pregnant rats, but did not differ between the groups of different gestational ages. Oestradiol significantly (P

Original languageEnglish
Pages (from-to)121-126
Number of pages6
JournalJournal of Endocrinology
Volume193
Issue number1
DOIs
Publication statusPublished - Apr 2007

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Oxytocin
Vasopressins
Uterus
Progesterone
Estradiol
Gene Expression
Pregnancy
Genes
Gestational Age
Posterior Pituitary Hormones
Messenger RNA
Myometrium
Reverse Transcription
Hormones
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Endocrinology

Cite this

Expression of the oxytocin gene, but not the vasopressin gene, in the rat uterus during pregnancy : Influence of oestradiol and progesterone. / Bossmar, Thomas; Osman, N.; Zilahi, E.; El Haj, M. A.; Nowotny, N.; Conlon, J. M.

In: Journal of Endocrinology, Vol. 193, No. 1, 04.2007, p. 121-126.

Research output: Contribution to journalArticle

Bossmar, Thomas ; Osman, N. ; Zilahi, E. ; El Haj, M. A. ; Nowotny, N. ; Conlon, J. M. / Expression of the oxytocin gene, but not the vasopressin gene, in the rat uterus during pregnancy : Influence of oestradiol and progesterone. In: Journal of Endocrinology. 2007 ; Vol. 193, No. 1. pp. 121-126.
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