Existing Challenges Associated with Offering Prenatal Genetic Diagnosis in an Arab Society in the Sultanate of Oman

Zandrè Bruwer, Udayakumar Achandira, Khalsa Al Kharousi, Adila Al-Kindy

Research output: Contribution to journalArticle

Abstract

The incidence of congenital anomalies and/or genetic disorders in the Omani population has reached figures greater than double the global statistics. Preference for consanguineous unions together with the fact that termination of pregnancy in Muslim communities are largely avoided, have been highlighted as contributing factors. This overview identifies a third significant aspect contributing to the elevated rate of genetic disorders in the Omani population. Namely, a lack of services that are able to offer termination of pregnancy for severe congenital anomalies, to requesting parents. In this report we select an unusual case of a family at risk for two distinct genetic disorders - 6q micro-deletion and unbalanced products of conception attributed to a balanced parental translocation involving chromosome 3 and 13, to portray and examine the current situation faced by Omani couples interested in prenatal diagnosis for termination of pregnancy. Additional challenges and pitfalls to developing a prenatal diagnostic service as part of the genetic service in Oman are discussed.

Original languageEnglish
Pages (from-to)928-932
Number of pages5
JournalJournal of Genetic Counseling
Volume23
Issue number6
DOIs
Publication statusPublished - Nov 16 2014

Fingerprint

Oman
Inborn Genetic Diseases
Prenatal Diagnosis
Pregnancy
Genetic Services
Diagnostic Services
Chromosomes, Human, Pair 13
Islam
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Chromosomes, Human, Pair 3
Population
Incidence

Keywords

  • 6q deletion
  • Genetic counseling
  • Islam
  • Prenatal
  • Termination of pregnancy
  • Translocation

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Existing Challenges Associated with Offering Prenatal Genetic Diagnosis in an Arab Society in the Sultanate of Oman. / Bruwer, Zandrè; Achandira, Udayakumar; Al Kharousi, Khalsa; Al-Kindy, Adila.

In: Journal of Genetic Counseling, Vol. 23, No. 6, 16.11.2014, p. 928-932.

Research output: Contribution to journalArticle

Bruwer, Zandrè ; Achandira, Udayakumar ; Al Kharousi, Khalsa ; Al-Kindy, Adila. / Existing Challenges Associated with Offering Prenatal Genetic Diagnosis in an Arab Society in the Sultanate of Oman. In: Journal of Genetic Counseling. 2014 ; Vol. 23, No. 6. pp. 928-932.
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