Ethanol-induced alteration in thiamin status of young turkey poults

Badreldin H. Ali, Caroline M. Czarnecki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

1. 1. The effect of ethanol on thiamin status was determined in the turkey poult, a new animal model for alcohol-induced cardiomyopathy in humans. 2. 2. The poults were given ethanol (4 to 5% v/v) in the drinking water for six weeks post-hatch. This treatment decreased body weights and increased significantly the relative weights of the hearts. 3. 3. Ethanol consumption increased significantly the blood concentrations of pyruvate and lactate, decreased the activity of erythrocyte transketolase (TK), and increased the stimulation of TK activity of thiamin pyrophosphate (TPP) in lyzed blood cells (TPP effect). 4. 4. These findings indicate that ethanol treatment has an adverse effect on the thiamin status of the turkey poult.

Original languageEnglish
Pages (from-to)119-121
Number of pages3
JournalGeneral Pharmacology
Volume18
Issue number2
DOIs
Publication statusPublished - 1987

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Thiamine
Ethanol
Transketolase
Thiamine Pyrophosphate
Pyruvic Acid
Cardiomyopathies
Drinking Water
Lactic Acid
Blood Cells
Animal Models
Erythrocytes
Body Weight
Alcohols
Weights and Measures

ASJC Scopus subject areas

  • Pharmacology

Cite this

Ethanol-induced alteration in thiamin status of young turkey poults. / Ali, Badreldin H.; Czarnecki, Caroline M.

In: General Pharmacology, Vol. 18, No. 2, 1987, p. 119-121.

Research output: Contribution to journalArticle

Ali, Badreldin H. ; Czarnecki, Caroline M. / Ethanol-induced alteration in thiamin status of young turkey poults. In: General Pharmacology. 1987 ; Vol. 18, No. 2. pp. 119-121.
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