TY - JOUR
T1 - Epidemiological pattern of classical Borna disease and regional genetic clustering of Borna disease viruses point towards the existence of to-date unknown endemic reservoir host populations
AU - Dürrwald, Ralf
AU - Kolodziejek, Jolanta
AU - Muluneh, Aemero
AU - Herzog, Sibylle
AU - Nowotny, Norbert
N1 - Funding Information:
The authors thank Dr. Heinrich Ihlenburg (Halle/Saale), Dr. Wolfgang Boden (Dessau), Dr. Wilhelm Bauer (Dessau), Dr. Hans Müller (Dessau), Dr. Werner Achtzehn (Barby), Dr. Guntram Hagemann, Dr. Andreas Neubert, and Dr. Margrit Gehrt (IDT, Rodleben) for their help in uncovering the history of the “Dessau” vaccine, Prof. Dr. Kurt Danner (Ravensburg) for information on vaccine use in West Germany, Dr. Franz Josef Pauels (Bayerische Tierseuchenkasse, Munich) for data on BD cases in Bavaria, Prof. Dr. Lothar Stitz (Institute of Immunology, Friedrich-Loeffler-Institute, Tübingen), Dr. Wolfgang Zimmermann (AGOWA GmbH, Berlin) and Prof. Dr. Herbert Weissenböck (Institute of Pathology and Forensic Veterinary Medicine, University of Veterinary Medicine, Vienna) for valuable information on BDV sequences, and Dr. Juan Carlos de la Torre (The Scripps Research Institute, La Jolla) and Prof. Dr. Felix Ehrensperger (Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich) for helpful discussions. We cordially thank Mrs. Helga Lussy (Zoonoses and Emerging Infections Group, Clinical Virology, University of Veterinary Medicine, Vienna) for excellent technical assistance. R.D. is grateful to Prof. Dr. Heinrich Liebermann, Steinach, for encouraging epidemiological studies on BD in the early 1990s and to the University of Leipzig for a grant from December 1990–March 1993 which supported him during the period of epidemiological investigations.
PY - 2006/3
Y1 - 2006/3
N2 - Classical Borna disease (cBD), a nonpurulent encephalitis of solipeds and sheep, is endemic in certain areas of central Europe. The etiologic agent is Borna disease virus (BDV), thus far the only member of the family Bornaviridae. Based on epidemiological patterns of cBD and recent phylogenetic findings this review hypothesizes the possible existence of yet unknown BDV reservoir host populations, and analyzes critically BDVs from outside endemic regions.
AB - Classical Borna disease (cBD), a nonpurulent encephalitis of solipeds and sheep, is endemic in certain areas of central Europe. The etiologic agent is Borna disease virus (BDV), thus far the only member of the family Bornaviridae. Based on epidemiological patterns of cBD and recent phylogenetic findings this review hypothesizes the possible existence of yet unknown BDV reservoir host populations, and analyzes critically BDVs from outside endemic regions.
KW - Borna disease virus
KW - Epidemiological pattern
KW - Etiology
KW - Genetic clustering
KW - Reservoir host population
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U2 - 10.1016/j.micinf.2005.08.013
DO - 10.1016/j.micinf.2005.08.013
M3 - Short survey
C2 - 16469519
AN - SCOPUS:33645462552
VL - 8
SP - 917
EP - 929
JO - Microbes and Infection
JF - Microbes and Infection
SN - 1286-4579
IS - 3
ER -