Elucidating the neuropsychological profile of apathetic syndrome and disinhibition syndrome in a brain-injured population in Oman

Samir Al-Adawi, Aziz Al-Naamani, Yahya Al-Farsi, Musthafa M. Essa, David T. Burke, May El-Bouri, Kerry Amstrong, Jason Edwards, Sura Al-Muscati, Aida Saihi MacFarland, Ali Al Maashani

Research output: Contribution to journalArticle

Abstract

Objective: The purpose of this study was to compare the neuropsychological performance of two frontal dysexecutive phenotypes - disinhibited' syndrome (DS) and 'apathetic' syndrome (AS) following a traumatic brain injury in a non-western population, Oman. Methods: The study compared the performance of DS and AS in neuropsychological measures including those tapping into verbal reasoning ability/working memory/attention planning/goal-directed behavior and affective ranges. Results: The present analysis showed that DS and AS participants did not differ on indices measuring working memory/attention and affective ranges. However, the two cohorts differed significantly in measures of planning/goal-directed behaviour. Conclusion: This study lays the groundwork for further scrutiny in delineating the different characteristics of what has been previously labelled as frontal dysexecutive phenotype. This study indicates that DS and AS are marked with specific neuropsychological deficits.

Original languageEnglish
Pages (from-to)35-45
Number of pages11
JournalInternational Journal of Nutrition, Pharmacology, Neurological Diseases
Volume6
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

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Oman
Brain
Population
Short-Term Memory
Phenotype
Aptitude

Keywords

  • Apathetic syndrome
  • cognitive measures
  • disinhibition syndrome
  • executive functioning
  • neuropsychology
  • Oman
  • traumatic brain injury

ASJC Scopus subject areas

  • Clinical Neurology
  • Pharmacology (medical)
  • Nutrition and Dietetics

Cite this

Elucidating the neuropsychological profile of apathetic syndrome and disinhibition syndrome in a brain-injured population in Oman. / Al-Adawi, Samir; Al-Naamani, Aziz; Al-Farsi, Yahya; Essa, Musthafa M.; Burke, David T.; El-Bouri, May; Amstrong, Kerry; Edwards, Jason; Al-Muscati, Sura; MacFarland, Aida Saihi; Al Maashani, Ali.

In: International Journal of Nutrition, Pharmacology, Neurological Diseases, Vol. 6, No. 1, 01.01.2016, p. 35-45.

Research output: Contribution to journalArticle

Al-Adawi, Samir ; Al-Naamani, Aziz ; Al-Farsi, Yahya ; Essa, Musthafa M. ; Burke, David T. ; El-Bouri, May ; Amstrong, Kerry ; Edwards, Jason ; Al-Muscati, Sura ; MacFarland, Aida Saihi ; Al Maashani, Ali. / Elucidating the neuropsychological profile of apathetic syndrome and disinhibition syndrome in a brain-injured population in Oman. In: International Journal of Nutrition, Pharmacology, Neurological Diseases. 2016 ; Vol. 6, No. 1. pp. 35-45.
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