Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex: Measurement, kinetic and thermodynamic studies

Emad A. Khudaish; Mohammed Al-Hinaai; Salim Al-Harthy; Karthik Laxman

doi:10.1016/j.electacta.2014.05.029

Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex: Measurement, kinetic and thermodynamic studies

Emad A. Khudaish^*, Mohammed Al-Hinaai, Salim Al-Harthy, Karthik Laxman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) ₃]^3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10^-5 cm² s^-1 and 3.21 × 10 ^-3 cm s^-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.

Original language	English
Pages (from-to)	319-326
Number of pages	8
Journal	Electrochimica Acta
Volume	135
DOIs	https://doi.org/10.1016/j.electacta.2014.05.029
Publication status	Published - Jul 20 2014

Keywords

Chlorpheniramine maleate
Polytyramine
Sensors
Tris(bipyridyl)ruthenium (II)

ASJC Scopus subject areas

Electrochemistry
Chemical Engineering(all)

Access to Document

10.1016/j.electacta.2014.05.029

Cite this

@article{5bfbb46bf6a14359805ddb7ce6658ddb,

title = "Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex: Measurement, kinetic and thermodynamic studies",

abstract = "A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) 3]3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10-5 cm2 s-1 and 3.21 × 10 -3 cm s-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.",

keywords = "Chlorpheniramine maleate, Polytyramine, Sensors, Tris(bipyridyl)ruthenium (II)",

author = "Khudaish, {Emad A.} and Mohammed Al-Hinaai and Salim Al-Harthy and Karthik Laxman",

year = "2014",

month = jul,

day = "20",

doi = "10.1016/j.electacta.2014.05.029",

language = "English",

volume = "135",

pages = "319--326",

journal = "Electrochimica Acta",

issn = "0013-4686",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex

T2 - Measurement, kinetic and thermodynamic studies

AU - Khudaish, Emad A.

AU - Al-Hinaai, Mohammed

AU - Al-Harthy, Salim

AU - Laxman, Karthik

PY - 2014/7/20

Y1 - 2014/7/20

N2 - A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) 3]3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10-5 cm2 s-1 and 3.21 × 10 -3 cm s-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.

AB - A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) 3]3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10-5 cm2 s-1 and 3.21 × 10 -3 cm s-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.

KW - Chlorpheniramine maleate

KW - Polytyramine

KW - Sensors

KW - Tris(bipyridyl)ruthenium (II)

UR - http://www.scopus.com/inward/record.url?scp=84901921099&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84901921099&partnerID=8YFLogxK

U2 - 10.1016/j.electacta.2014.05.029

DO - 10.1016/j.electacta.2014.05.029

M3 - Article

AN - SCOPUS:84901921099

VL - 135

SP - 319

EP - 326

JO - Electrochimica Acta

JF - Electrochimica Acta

SN - 0013-4686

ER -

Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex: Measurement, kinetic and thermodynamic studies

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this