Abstract
A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) 3]3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10-5 cm2 s-1 and 3.21 × 10 -3 cm s-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.
| Original language | English |
|---|---|
| Pages (from-to) | 319-326 |
| Number of pages | 8 |
| Journal | Electrochimica Acta |
| Volume | 135 |
| DOIs | |
| Publication status | Published - Jul 20 2014 |
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Keywords
- Chlorpheniramine maleate
- Polytyramine
- Sensors
- Tris(bipyridyl)ruthenium (II)
ASJC Scopus subject areas
- Electrochemistry
- Chemical Engineering(all)
Cite this
Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex : Measurement, kinetic and thermodynamic studies. / Khudaish, Emad A.; Al-Hinaai, Mohammed; Al-Harthy, Salim; Laxman, Karthik.
In: Electrochimica Acta, Vol. 135, 20.07.2014, p. 319-326.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrochemical oxidation of chlorpheniramine at polytyramine film doped with ruthenium (II) complex
T2 - Measurement, kinetic and thermodynamic studies
AU - Khudaish, Emad A.
AU - Al-Hinaai, Mohammed
AU - Al-Harthy, Salim
AU - Laxman, Karthik
PY - 2014/7/20
Y1 - 2014/7/20
N2 - A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) 3]3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10-5 cm2 s-1 and 3.21 × 10 -3 cm s-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.
AB - A solid-state sensor based on polytyramine film deposited at glassy carbon electrode doped with tris(2,2′-bipyridyl)Ru(II) complex (Ru/Pty/GCE) was constructed electrochemically. A redox property represented by [Ru(bpy) 3]3+/2+ couple immobilized at the Pty moiety was characterized using typical voltammetric techniques. The XPS data and AFM images confirm the grafting of Ru species on the top of Pty while the electrochemical impedance spectroscopy (EIS) data supports the immobilization of both surface modifiers onto the GCE. The constructed sensor exhibits a substantial reactivity, stability and high sensitivity to chlorpheniramine maleate (CPM) oxidation. The detection limit (S/N = 3) was brought down to 338 nM using differential pulse voltammetry method. Thermodynamic and kinetic parameters were evaluated using hydrodynamic method. The apparent diffusion coefficient and the heterogeneous electron transfer rate constant for the CPM oxidation were 2.67 × 10-5 cm2 s-1 and 3.21 × 10 -3 cm s-1, respectively. Interference studies and real sample analysis were conducted with excellent performance and satisfactory results.
KW - Chlorpheniramine maleate
KW - Polytyramine
KW - Sensors
KW - Tris(bipyridyl)ruthenium (II)
UR - http://www.scopus.com/inward/record.url?scp=84901921099&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901921099&partnerID=8YFLogxK
U2 - 10.1016/j.electacta.2014.05.029
DO - 10.1016/j.electacta.2014.05.029
M3 - Article
VL - 135
SP - 319
EP - 326
JO - Electrochimica Acta
JF - Electrochimica Acta
SN - 0013-4686
ER -