TY - JOUR
T1 - Effects of Frankincense Compounds on Infection, Inflammation, and Oral Health
AU - Almeida-Da-silva, Cássio Luiz Coutinho
AU - Sivakumar, Nallusamy
AU - Asadi, Homer
AU - Chang-Chien, Anna
AU - Qoronfleh, M. Walid
AU - Ojcius, David M.
AU - Essa, Musthafa Mohamed
N1 - Funding Information:
This research was supported by intramural funds from the University of the Pacific to DMO and CLCAS (Start-Up Funds D30059—Activity 101).
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/6/29
Y1 - 2022/6/29
N2 - Boswellia trees, found throughout the Middle East and parts of Africa and Asia, are the source of frankincense oil. Since antiquity, frankincense has been traded as a precious commodity, but it has also been used for the treatment of chronic disease, inflammation, oral health, and microbial infection. More recently, the bioactive components of Boswellia trees have been identified and characterized for their effects on cancer, microbial infection (especially infection by oral pathogens), and inflammation. Most studies have focused on cell lines, but more recent research has also investigated effects in animal models of disease. As natural products are considered to be safer than synthetic drugs, there is growing interest in further developing the use of substances such as frankincense oil for therapeutic treatment.
AB - Boswellia trees, found throughout the Middle East and parts of Africa and Asia, are the source of frankincense oil. Since antiquity, frankincense has been traded as a precious commodity, but it has also been used for the treatment of chronic disease, inflammation, oral health, and microbial infection. More recently, the bioactive components of Boswellia trees have been identified and characterized for their effects on cancer, microbial infection (especially infection by oral pathogens), and inflammation. Most studies have focused on cell lines, but more recent research has also investigated effects in animal models of disease. As natural products are considered to be safer than synthetic drugs, there is growing interest in further developing the use of substances such as frankincense oil for therapeutic treatment.
KW - frankincense
KW - immunology
KW - infection
KW - inflammation
KW - microbiology
KW - oral health
KW - Trees
KW - Animals
KW - Frankincense/pharmacology
KW - Boswellia
KW - Inflammation/drug therapy
KW - Oral Health
UR - http://www.scopus.com/inward/record.url?scp=85133495812&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85133495812&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/4d62cff7-35c5-360f-bbc3-8f151d6f015a/
U2 - 10.3390/molecules27134174
DO - 10.3390/molecules27134174
M3 - Article
C2 - 35807419
AN - SCOPUS:85133495812
SN - 1420-3049
VL - 27
JO - Molecules
JF - Molecules
IS - 13
M1 - 4174
ER -
