TY - JOUR
T1 - Effect of suboptimal breast-feeding on occurrence of autism
T2 - A case-control study
AU - Al-Farsi, Yahya M.
AU - Al-Sharbati, Marwan M.
AU - Waly, Mostafa I.
AU - Al-Farsi, Omar A.
AU - Al-Shafaee, Mohammed A.
AU - Al-Khaduri, Maha M.
AU - Trivedi, Malav S.
AU - Deth, Richard C.
PY - 2012/7
Y1 - 2012/7
N2 - Objective: To evaluate the association between suboptimal breast-feeding practices and autism spectrum disorders (ASDs). Methods: A case-control study was conducted in 102 ASD cases and 102 matched healthy controls. Results: Based on adjusted odds ratios from logistic regression models, ASD was found to be associated with the late initiation of breast-feeding (odds ratio 1.48, 95% confidence interval 1.01-3.1), a non-intake of colostrum (odds ratio 1.7, 95% confidence interval 1.03-4.3), prelacteal feeding, and bottle-feeding. The risk of ASD was found to decrease in a dose-response fashion over increasing periods of exclusive breast-feeding (P for trend = 0.04) and continued breast-feeding (P for trend = 0.001). Conclusion: The study indicates that increased ASD risk is generally associated with suboptimal breast-feeding practices.
AB - Objective: To evaluate the association between suboptimal breast-feeding practices and autism spectrum disorders (ASDs). Methods: A case-control study was conducted in 102 ASD cases and 102 matched healthy controls. Results: Based on adjusted odds ratios from logistic regression models, ASD was found to be associated with the late initiation of breast-feeding (odds ratio 1.48, 95% confidence interval 1.01-3.1), a non-intake of colostrum (odds ratio 1.7, 95% confidence interval 1.03-4.3), prelacteal feeding, and bottle-feeding. The risk of ASD was found to decrease in a dose-response fashion over increasing periods of exclusive breast-feeding (P for trend = 0.04) and continued breast-feeding (P for trend = 0.001). Conclusion: The study indicates that increased ASD risk is generally associated with suboptimal breast-feeding practices.
KW - Autism
KW - Autism spectrum disorder
KW - Oman
KW - Suboptimal breast-feeding
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UR - http://www.scopus.com/inward/citedby.url?scp=84862237742&partnerID=8YFLogxK
U2 - 10.1016/j.nut.2012.01.007
DO - 10.1016/j.nut.2012.01.007
M3 - Article
C2 - 22541054
AN - SCOPUS:84862237742
SN - 0899-9007
VL - 28
SP - e27-e32
JO - Nutrition
JF - Nutrition
IS - 7-8
ER -
