Effect of high parity on the occurrence of prediabetes

A cohort study

Yahya M. Al-Farsi, Daniel R. Brooks, Martha M. Werler, Howard J. Cabral, Mohammed A. Al-Shafei, Henk C. Wallenburg

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (

Original languageEnglish
Pages (from-to)1182-1186
Number of pages5
JournalActa Obstetricia et Gynecologica Scandinavica
Volume89
Issue number9
DOIs
Publication statusPublished - 2010

Fingerprint

Prediabetic State
Parity
Cohort Studies
Pregnancy
Oman
Maternal Age
Glucose Tolerance Test
Type 2 Diabetes Mellitus
Fasting
Retrospective Studies
Regression Analysis
Outcome Assessment (Health Care)
Education
Glucose
Population

Keywords

  • AMAL study
  • Cox proportional hazards model
  • Directed acyclic graphs
  • Epidemiologic confounding
  • High parity
  • Prediabetes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Medicine(all)

Cite this

Effect of high parity on the occurrence of prediabetes : A cohort study. / Al-Farsi, Yahya M.; Brooks, Daniel R.; Werler, Martha M.; Cabral, Howard J.; Al-Shafei, Mohammed A.; Wallenburg, Henk C.

In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 89, No. 9, 2010, p. 1182-1186.

Research output: Contribution to journalArticle

Al-Farsi, Yahya M. ; Brooks, Daniel R. ; Werler, Martha M. ; Cabral, Howard J. ; Al-Shafei, Mohammed A. ; Wallenburg, Henk C. / Effect of high parity on the occurrence of prediabetes : A cohort study. In: Acta Obstetricia et Gynecologica Scandinavica. 2010 ; Vol. 89, No. 9. pp. 1182-1186.
@article{5e39ad442d1d45c1ae49f749cbcf115a,
title = "Effect of high parity on the occurrence of prediabetes: A cohort study",
abstract = "Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (",
keywords = "AMAL study, Cox proportional hazards model, Directed acyclic graphs, Epidemiologic confounding, High parity, Prediabetes",
author = "Al-Farsi, {Yahya M.} and Brooks, {Daniel R.} and Werler, {Martha M.} and Cabral, {Howard J.} and Al-Shafei, {Mohammed A.} and Wallenburg, {Henk C.}",
year = "2010",
doi = "10.3109/00016349.2010.501854",
language = "English",
volume = "89",
pages = "1182--1186",
journal = "Acta Obstetricia et Gynecologica Scandinavica",
issn = "0001-6349",
publisher = "Wiley-Blackwell",
number = "9",

}

TY - JOUR

T1 - Effect of high parity on the occurrence of prediabetes

T2 - A cohort study

AU - Al-Farsi, Yahya M.

AU - Brooks, Daniel R.

AU - Werler, Martha M.

AU - Cabral, Howard J.

AU - Al-Shafei, Mohammed A.

AU - Wallenburg, Henk C.

PY - 2010

Y1 - 2010

N2 - Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (

AB - Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (

KW - AMAL study

KW - Cox proportional hazards model

KW - Directed acyclic graphs

KW - Epidemiologic confounding

KW - High parity

KW - Prediabetes

UR - http://www.scopus.com/inward/record.url?scp=77956307553&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77956307553&partnerID=8YFLogxK

U2 - 10.3109/00016349.2010.501854

DO - 10.3109/00016349.2010.501854

M3 - Article

VL - 89

SP - 1182

EP - 1186

JO - Acta Obstetricia et Gynecologica Scandinavica

JF - Acta Obstetricia et Gynecologica Scandinavica

SN - 0001-6349

IS - 9

ER -