Abstract
Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (
| Original language | English |
|---|---|
| Pages (from-to) | 1182-1186 |
| Number of pages | 5 |
| Journal | Acta Obstetricia et Gynecologica Scandinavica |
| Volume | 89 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2010 |
Fingerprint
Keywords
- AMAL study
- Cox proportional hazards model
- Directed acyclic graphs
- Epidemiologic confounding
- High parity
- Prediabetes
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Medicine(all)
Cite this
Effect of high parity on the occurrence of prediabetes : A cohort study. / Al-Farsi, Yahya M.; Brooks, Daniel R.; Werler, Martha M.; Cabral, Howard J.; Al-Shafei, Mohammed A.; Wallenburg, Henk C.
In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 89, No. 9, 2010, p. 1182-1186.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of high parity on the occurrence of prediabetes
T2 - A cohort study
AU - Al-Farsi, Yahya M.
AU - Brooks, Daniel R.
AU - Werler, Martha M.
AU - Cabral, Howard J.
AU - Al-Shafei, Mohammed A.
AU - Wallenburg, Henk C.
PY - 2010
Y1 - 2010
N2 - Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (
AB - Objective. To assess the effect of parity on the occurrence of prediabetes defined as an abnormal fasting plasma glucose (5.66.9 mmol/l), an abnormal 2-hour oral glucose tolerance test (7.711.1 mmol/l), or both, before 12 weeks gestation or at least 6 weeks after delivery. Design. Retrospective cohort study. Setting. Nested on a community trial Delaying the Development of Diabetes Mellitus type 2 (AMAL study) in Oman. Population. 532 women with a total of 3,196 pregnancies. Methods. We conducted sets of Cox proportional hazard regression analyses: crude, age-adjusted and full models which adjusted for maternal age, education, family income and year of delivery. Main outcome measures. Hazard ratio (HR) of the effect of parity on prediabetes. Results. We enumerated 258 cases of prediabetes over 8,529 person-years of follow up. In the crude model, high parity (≥5) pregnancies carried a higher risk of prediabetes than low parity (
KW - AMAL study
KW - Cox proportional hazards model
KW - Directed acyclic graphs
KW - Epidemiologic confounding
KW - High parity
KW - Prediabetes
UR - http://www.scopus.com/inward/record.url?scp=77956307553&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77956307553&partnerID=8YFLogxK
U2 - 10.3109/00016349.2010.501854
DO - 10.3109/00016349.2010.501854
M3 - Article
VL - 89
SP - 1182
EP - 1186
JO - Acta Obstetricia et Gynecologica Scandinavica
JF - Acta Obstetricia et Gynecologica Scandinavica
SN - 0001-6349
IS - 9
ER -