Effect of hemolysis on plasma cardiac troponin levels at clinically relevant concentrations: An experimental study

Maya Al-Shidhani; Huda Al Saadi; Waad Allah Mula-Abed; Nafila B. Al Riyami

doi:10.4172/0974-8369.1000217

Effect of hemolysis on plasma cardiac troponin levels at clinically relevant concentrations: An experimental study

Maya Al-Shidhani, Huda Al Saadi, Waad Allah Mula-Abed, Nafila B. Al Riyami^*

^*Corresponding author for this work

Biochemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Hemolysis is one of the most commonly encountered pre-analytical sources of interference in the Clinical Biochemistry laboratory. Hemolysis is known to cause a variable interference in both cardiac troponin I (cTnI) and troponin T (cTnT) assays. Each laboratory should determine and publicize these effects. In this experimental study we determined the effect of in-vitro sample hemolysis on both types of cardiac troponin assays and whether the effect was clinically significant.

Original language	English
Article number	1000217
Journal	Biology and Medicine
Volume	6
Issue number	4
DOIs	https://doi.org/10.4172/0974-8369.1000217
Publication status	Published - 2014

Keywords

Cardiac troponin
Hemolysis
Interference
Oman
cTnI
cTnT

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.4172/0974-8369.1000217

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title = "Effect of hemolysis on plasma cardiac troponin levels at clinically relevant concentrations: An experimental study",

abstract = "Hemolysis is one of the most commonly encountered pre-analytical sources of interference in the Clinical Biochemistry laboratory. Hemolysis is known to cause a variable interference in both cardiac troponin I (cTnI) and troponin T (cTnT) assays. Each laboratory should determine and publicize these effects. In this experimental study we determined the effect of in-vitro sample hemolysis on both types of cardiac troponin assays and whether the effect was clinically significant.",

keywords = "Cardiac troponin, Hemolysis, Interference, Oman, cTnI, cTnT",

author = "Maya Al-Shidhani and {Al Saadi}, Huda and Mula-Abed, {Waad Allah} and {Al Riyami}, {Nafila B.}",

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AU - Al-Shidhani, Maya

AU - Al Saadi, Huda

AU - Mula-Abed, Waad Allah

AU - Al Riyami, Nafila B.

PY - 2014

Y1 - 2014

N2 - Hemolysis is one of the most commonly encountered pre-analytical sources of interference in the Clinical Biochemistry laboratory. Hemolysis is known to cause a variable interference in both cardiac troponin I (cTnI) and troponin T (cTnT) assays. Each laboratory should determine and publicize these effects. In this experimental study we determined the effect of in-vitro sample hemolysis on both types of cardiac troponin assays and whether the effect was clinically significant.

AB - Hemolysis is one of the most commonly encountered pre-analytical sources of interference in the Clinical Biochemistry laboratory. Hemolysis is known to cause a variable interference in both cardiac troponin I (cTnI) and troponin T (cTnT) assays. Each laboratory should determine and publicize these effects. In this experimental study we determined the effect of in-vitro sample hemolysis on both types of cardiac troponin assays and whether the effect was clinically significant.

KW - Cardiac troponin

KW - Hemolysis

KW - Interference

KW - Oman

KW - cTnI

KW - cTnT

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ER -

Effect of hemolysis on plasma cardiac troponin levels at clinically relevant concentrations: An experimental study

Abstract

Keywords

ASJC Scopus subject areas

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