Effect of hemolysis on plasma cardiac troponin levels at clinically relevant concentrations: An experimental study

Maya Al-Shidhani, Huda Al Saadi, Waad Allah Mula-Abed, Nafila B. Al Riyami

Research output: Contribution to journalArticle

Abstract

Hemolysis is one of the most commonly encountered pre-analytical sources of interference in the Clinical Biochemistry laboratory. Hemolysis is known to cause a variable interference in both cardiac troponin I (cTnI) and troponin T (cTnT) assays. Each laboratory should determine and publicize these effects. In this experimental study we determined the effect of in-vitro sample hemolysis on both types of cardiac troponin assays and whether the effect was clinically significant.

Original languageEnglish
Article number1000217
JournalBiology and Medicine
Volume6
Issue number4
DOIs
Publication statusPublished - 2014

Keywords

  • Cardiac troponin
  • cTnI
  • cTnT
  • Hemolysis
  • Interference
  • Oman

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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